Panchal Zoë, Sakai Joseph T, Ellingson Jarrod M, Zellers Stephanie, Wright Kenneth P, McGue Matt K, Vrieze Scott, Hewitt John K, Corley Robin P, Iacono William, Hopfer Christian J, Ross J Megan
Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
J Psychoactive Drugs. 2025 Mar 27:1-10. doi: 10.1080/02791072.2025.2484379.
We examined the association of recreational cannabis legalization (RCL) with frequency of using cannabis, alcohol, and sleep medication for sleep and with co-use of cannabis with other sleep aids. We used linear regression models to examine these associations in a population-based sample of adult twins ( = 3,141). Participants (M = 37 (SD = 5)) were primarily White (93%), with 5% Hispanic/Latinx, and female (61%). RCL was associated with using cannabis for sleep more frequently even after controlling for cohort, demographics, sleep quality, anxiety, depression, physical health, season, and pre-legalization cannabis use frequency (β = 0.123, = .001). RCL was not associated with frequency of using alcohol or sleep medication for sleep, or with co-use of cannabis and other sleep aids. More research is needed to determine whether RCL leads to more frequent use of cannabis for sleep.
我们研究了娱乐用大麻合法化（RCL）与使用大麻、酒精和助眠药物助眠的频率之间的关联，以及大麻与其他助眠药物同时使用的情况。我们使用线性回归模型，在一个基于人群的成年双胞胎样本（n = 3141）中研究这些关联。参与者的年龄中位数为37岁（标准差 = 5），主要为白人（93%），5%为西班牙裔/拉丁裔，女性占61%。即使在控制了队列、人口统计学特征、睡眠质量、焦虑、抑郁、身体健康状况、季节以及合法化前的大麻使用频率之后，RCL仍与更频繁地使用大麻助眠有关（β = 0.123，p = 0.001）。RCL与使用酒精或助眠药物助眠的频率，以及与大麻和其他助眠药物同时使用均无关联。需要更多研究来确定RCL是否会导致更频繁地使用大麻助眠。
