Weisberg L A, Gerard G, Stazio A
Department of Neurology and Psychiatry, Tulane Medical Center, New Orleans, LA 70112.
Comput Med Imaging Graph. 1988 Jul-Aug;12(4):249-54. doi: 10.1016/0895-6111(86)90008-x.
This paper discusses the conditions which may be associated with diffuse periventricular hypodensity on CT. Of these conditions, subacute arteriosclerotic encephalopathy (Binswanger's disease) is a common differential diagnostic consideration. This condition results from ischemic demyelination with loss of axons and astrogliosis. CT usually shows diffuse bilateral confluent hypodensities in the cerebral white matter. This is most prominent and seen earliest in the periventricular region and may extend more diffusely into the centrum semiovale. It is important to differentiate this condition from normal pressure hydrocephalus and primary nonischemic demyelinating disease (multiple sclerosis).
本文讨论了可能与CT上脑室周围弥漫性低密度相关的情况。在这些情况中，亚急性动脉硬化性脑病（宾斯旺格病）是常见的鉴别诊断考虑因素。这种情况是由缺血性脱髓鞘伴轴突丢失和星形胶质细胞增生引起的。CT通常显示脑白质内双侧弥漫性融合性低密度。这在脑室周围区域最为明显且最早出现，并可能更广泛地延伸至半卵圆中心。将这种情况与正常压力脑积水和原发性非缺血性脱髓鞘疾病（多发性硬化症）区分开来很重要。
