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HIV 阳性的男男性行为者在性行为中使用药物和出现精神病理学症状( slamsex ):来自 U-SEX GESIDA 9416 研究的数据。

Drug-related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (slamsex): Data from the U-SEX GESIDA 9416 Study.

机构信息

Psychiatry Service, Henares University Hospital, Madrid, Spain.

Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain.

出版信息

PLoS One. 2019 Dec 4;14(12):e0220272. doi: 10.1371/journal.pone.0220272. eCollection 2019.

DOI:10.1371/journal.pone.0220272
PMID:31800575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6892548/
Abstract

OBJECTIVES

Sexualized intravenous drug use, also known as slamsex, seems to be increasing among HIV-positive men who have sex with men (MSM). Physical and psychopathological symptoms have previously been reported in this population, although research on the subject of slamsex is scarce. The objectives of our study were to describe the psychopathological background of a sample of HIV-positive MSM who engaged in slamsex during the previous year and to compare physical, psychopathological, and drug-related symptoms between these participants and those who engaged in non-injecting sexualized drug use.

DESIGN AND METHODS

Participants (HIV-positive MSM) were recruited from the U-Sex study in 22 HIV clinics in Madrid during 2016-17. All participants completed an anonymous cross-sectional online survey on sexual behavior and recreational drug use. When participants met the inclusion criteria, physicians offered them the opportunity to participate and gave them a card with a unique code and a link to access the online survey. The present analysis is based on HIV-positive MSM who had engaged in slamsex and non-injecting sexualized drug use.

RESULTS

The survey sample comprised 742 participants. Of all the participants who completed the survey, 216 (29.1%) had engaged in chemsex, and of these, 34 (15.7%) had engaged in slamsex. Participants who engaged in slamsex were more likely to have current psychopathology (depression, anxiety, and drug-related disorders) than participants who engaged in non-injecting sexualized drug use. In addition, participants who engaged in slamsex more frequently reported high-risk sexual behaviors and polydrug use and were more often diagnosed with sexually transmitted infections (STIs) and hepatitis C than those who did not inject drugs. Compared with participants who did not inject drugs, participants who engaged in slamsex experienced more severe drug-related symptoms (withdrawal and dependence), symptoms of severe intoxication (loss of consciousness), and severe psychopathological symptoms during or after slamsex (eg, paranoid thoughts and suicidal behaviors).

CONCLUSION

Slamsex is closely associated with current psychiatric disorders and severe drug-related and psychiatric symptoms.

摘要

目的

性注射吸毒,也称为 slamsex,似乎在 HIV 阳性男男性行为者(MSM)中越来越普遍。尽管之前已经报道了该人群的身体和精神病理学症状,但 slamsex 相关研究很少。我们的研究目的是描述在过去一年中进行 slamsex 的 HIV 阳性 MSM 样本的精神病理学背景,并比较这些参与者与进行非注射性性药物使用者的身体、精神病理学和药物相关症状。

设计和方法

参与者(HIV 阳性 MSM)于 2016-17 年期间从马德里的 22 家 HIV 诊所的 U-Sex 研究中招募。所有参与者都完成了一项关于性行为和娱乐性药物使用的匿名横断面在线调查。当参与者符合纳入标准时,医生为他们提供了参与的机会,并给了他们一张带有唯一代码和访问在线调查链接的卡片。本分析基于曾进行 slamsex 和非注射性性药物使用的 HIV 阳性 MSM。

结果

调查样本包括 742 名参与者。在完成调查的所有参与者中,有 216 人(29.1%)曾进行过化学性行为,其中 34 人(15.7%)曾进行过 slamsex。与进行非注射性性药物使用者相比,进行 slamsex 的参与者更有可能出现当前的精神病理学(抑郁、焦虑和药物相关障碍)。此外,进行 slamsex 的参与者更频繁地报告高风险性行为和多药使用,并且更经常被诊断出患有性传播感染(STI)和丙型肝炎,而不是不注射毒品的参与者。与不注射毒品的参与者相比,进行 slamsex 的参与者在 slamsex 期间或之后经历了更严重的药物相关症状(戒断和依赖)、严重中毒症状(失去意识)和严重的精神病理学症状(如偏执思维和自杀行为)。

结论

slamsex 与当前的精神障碍以及严重的药物相关和精神病理学症状密切相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/19638b216267/pone.0220272.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/d5eb0ec22fc6/pone.0220272.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/48dd38595b96/pone.0220272.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/ef9c0638af24/pone.0220272.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/19638b216267/pone.0220272.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/d5eb0ec22fc6/pone.0220272.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/48dd38595b96/pone.0220272.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/ef9c0638af24/pone.0220272.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c72/6892548/19638b216267/pone.0220272.g004.jpg

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