School of Social Work, Columbia University, New York, New York.
Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
Depress Anxiety. 2020 Jan;37(1):81-89. doi: 10.1002/da.22981. Epub 2019 Dec 5.
Prolonged grief disorder (PGD) is a new diagnosis in the 11th edition of the International Classification of Diseases, estimated to affect 1 in 10 bereaved people and causing significant distress and impairment. Maladaptive thoughts play an important role in PGD. We have previously validated the typical beliefs questionnaire (TBQ), which contains five kinds of thinking commonly seen in PGD: protesting the death, negative thoughts about the world, needing the person, less grief is wrong, and grieving too much. The current paper examines the role of maladaptive cognition as measured by the TBQ in PGD and its change with treatment.
Among participants in a multisite clinical trial including 394 adults, we examined (a) the relationship between maladaptive thoughts at baseline and treatment outcomes, (b) the relationship between maladaptive thoughts and suicidality at baseline and posttreatment, and (c) the effect of treatment with and without complicated grief therapy (CGT) on maladaptive thinking.
TBQ scores were associated with treatment outcomes and were strongly related to suicidal thinking before and after treatment. TBQ scores showed significantly greater reduction in participants who received CGT with citalopram versus citalopram alone (adjusted mean standard error [SE] difference, -2.45 [0.85]; p = .004) and those who received CGT with placebo versus placebo alone (adjusted mean [SE] difference, -3.44 [0.90]; p < .001).
Maladaptive thoughts, as measured by the TBQ, have clinical and research significance for PGD and its treatment.
延长哀伤障碍(PGD)是《国际疾病分类》第 11 版中的一个新诊断,据估计,10 个丧亲的人中就有 1 个会受到影响,导致明显的痛苦和障碍。适应不良的思维在 PGD 中起着重要作用。我们之前已经验证了典型信念问卷(TBQ),其中包含五种在 PGD 中常见的思维:对死亡的抗议、对世界的负面想法、需要这个人、悲伤太少是错误的、悲伤过度。目前的研究探讨了 TBQ 测量的适应不良认知在 PGD 及其随治疗的变化中的作用。
在包括 394 名成年人的多地点临床试验参与者中,我们检查了:(a)基线时的适应不良思维与治疗结果之间的关系;(b)基线时的适应不良思维与治疗后自杀的关系;(c)接受和不接受复杂哀伤治疗(CGT)的治疗对适应不良思维的影响。
TBQ 评分与治疗结果相关,与治疗前后的自杀思维密切相关。与接受西酞普兰加 CGT 治疗的参与者相比(调整后的平均标准误差[SE]差异,-2.45 [0.85];p=0.004)和接受安慰剂加 CGT 治疗的参与者相比(调整后的平均[SE]差异,-3.44 [0.90];p<0.001),接受 CGT 加西酞普兰治疗的参与者的 TBQ 评分显著降低。
TBQ 测量的适应不良思维对 PGD 及其治疗具有临床和研究意义。