Smith Kirsten V, Thew Graham R, Carr Sarah C, Congrave Paris R, Rudge Susie, Thompson Erin H
Department of Experimental Psychology, University of Oxford, Oxford, UK.
Oxford Health NHS Foundation Trust, Oxford, UK.
Eur J Psychotraumatol. 2025 Dec;16(1):2545144. doi: 10.1080/20008066.2025.2545144. Epub 2025 Sep 2.
Individuals bereaved by cancer face significant emotional challenges, often experiencing prolonged grief disorder (PGD), PTSD, depression, and anxiety. Effective interventions are needed to target these mental health problems. This study evaluates the outcomes of the specialist bereavement charity, The Loss Foundation's therapeutic group intervention designed for individuals grieving a cancer-related loss. A total of 68 participants, enrolled across five cohorts, received a short-term group intervention targeting cognitive-behavioural factors and self-compassion. Due to recruitment limitations, randomized analyses were underpowered, therefore a broader service evaluation was performed, combining data from 2016 and 2018 cohorts. The primary outcome was PGD symptoms measured by the PG-13, with secondary outcomes examining PTSD, depression, anxiety, and self-compassion. Process measures were memory characteristics, grief appraisals, maladaptive coping strategies, and social disconnection. Data were analysed using linear mixed-effects models. Significant reductions were observed in symptoms of PGD ( = 0.65 at 3-month follow-up), PTSD, depression, and anxiety, with improvements in self-compassion ( = 0.53). Cognitive-behavioural process measures also showed significant changes, particularly in memory characteristics and negative appraisals, though social disconnection did not significantly change. Exploratory analyses indicated that lower baseline negative appraisals predicted better treatment outcomes. Attrition was minimal after the intervention began, though approximately 25% of participants did not provide follow-up data. The group intervention demonstrated positive effects on grief-related and mental health outcomes, supporting the use of cognitive-behavioural approaches in cancer bereavement. However, further randomized trials with larger samples are needed to confirm these findings and address limitations related to randomization and data completeness.
因癌症失去亲人的个体面临着重大的情感挑战,常常经历持续性悲伤障碍(PGD)、创伤后应激障碍(PTSD)、抑郁和焦虑。需要有效的干预措施来解决这些心理健康问题。本研究评估了专业丧亲慈善机构“失落基金会”为因癌症相关损失而悲伤的个体设计的治疗性团体干预的效果。共有68名参与者分五组入组,接受了针对认知行为因素和自我同情的短期团体干预。由于招募限制,随机分析的效力不足,因此进行了更广泛的服务评估,合并了2016年和2018年组的数据。主要结局是用PG-13量表测量的PGD症状,次要结局包括检查PTSD、抑郁、焦虑和自我同情。过程指标包括记忆特征、悲伤评估、适应不良的应对策略和社交脱节。使用线性混合效应模型分析数据。观察到PGD症状(3个月随访时效应量=0.65)、PTSD、抑郁和焦虑有显著降低,自我同情有所改善(效应量=0.53)。认知行为过程指标也显示出显著变化,特别是在记忆特征和消极评估方面,尽管社交脱节没有显著变化。探索性分析表明,较低的基线消极评估预示着更好的治疗效果。干预开始后的失访率很低,不过约25%的参与者未提供随访数据。团体干预对与悲伤相关的心理健康结局显示出积极影响,支持在癌症丧亲问题中使用认知行为方法。然而,需要进一步进行更大样本的随机试验来证实这些发现,并解决与随机化和数据完整性相关的局限性。