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自发性高血压大鼠和正常血压大鼠(褐家鼠)杠杆按压回避行为的对比

Contrasting lever-press avoidance behaviors of spontaneously hypertensive and normotensive rats (Rattus norvegicus).

作者信息

Berger D F, Starzec J J

机构信息

Psychology Department, State University of New York, Cortland 13045.

出版信息

J Comp Psychol. 1988 Sep;102(3):279-86. doi: 10.1037/0735-7036.102.3.279.

DOI:10.1037/0735-7036.102.3.279
PMID:3180735
Abstract

Lever-press avoidance performances of Spontaneously Hypertensive (SHR) and Wistar-Kyoto (WKY) rats were observed in two experiments. The first compared them at shock intensities of 1 or 2 mA. The SHRs had the highest percentage of avoidances, made the most coping responses (avoidances plus escapes), and received the fewest shocks (ps less than .05). They also had shorter avoidance and initial-escape latencies (ps less than .05). In the second experiment these strains were trained with signal-shock intervals that produce good (60 s) or poor (10 s) avoidance acquisition. Analysis of the Strain x Conditions x Blocks interaction showed that SHRs performed better with the longer interval (p less than .05), whereas WKYs' performance was similar with both (p greater than .05). Thus WKYs differed from all other strains previously exposed to these conditions. The findings are interpreted in terms that emphasize the SHRs' tendency to move, compared with the WKYs' tendency to freeze in response to aversive stimuli, rather than characterizing SHRs as hyperreactive.

摘要

在两项实验中观察了自发性高血压大鼠(SHR)和Wistar-Kyoto大鼠(WKY)的杠杆按压回避行为。第一项实验在1或2毫安的电击强度下对它们进行比较。SHR的回避百分比最高,做出的应对反应(回避加逃脱)最多,受到的电击最少(p小于0.05)。它们的回避潜伏期和初始逃脱潜伏期也较短(p小于0.05)。在第二项实验中,用产生良好(60秒)或较差(10秒)回避习得的信号-电击间隔对这些品系进行训练。对品系×条件×区组交互作用的分析表明,SHR在较长间隔下表现更好(p小于0.05),而WKY在两种间隔下的表现相似(p大于0.05)。因此,WKY与之前暴露于这些条件下的所有其他品系不同。这些发现的解释强调了与WKY对厌恶刺激做出冻结反应的倾向相比,SHR有移动的倾向,而不是将SHR描述为反应过度。

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