包虫病在藏区的疾病负担——中国西部欠发达地区的一个重大公共卫生问题。

Disease burden of echinococcosis in Tibetan communities-A significant public health issue in an underdeveloped region of western China.

机构信息

Institute for Parasitic Diseases Control, Chengdu, Sichuan, 610041, China.

Ultrasonography Department, Chengdu, Sichuan, 610041, China.

出版信息

Acta Trop. 2020 Mar;203:105283. doi: 10.1016/j.actatropica.2019.105283. Epub 2019 Dec 5.

Abstract

Echinococcosis is considered by the World Health Organization (WHO) to be a neglected zoonotic disease in the world. Some Tibetan communities were found to be highly endemic for echinococcosis just 20 years ago. Until recently, we were able to understand the overall disease burden of echinococcosis in Tibetan communities after prevalence data being available from nationwide investigations from 2012 to 2016. Data were abstracted from 9 publications regarding to echinococcosis prevalence between 2016-2018; from 10 data bases on echinococcosis prevalence for 151 Tibetan counties; and statistics of population, Gross Domestic Product (GDP) and health staff from 44 local statistic bureaus and government websites at provincial, prefecture and county level, and 2 books of provincial yearly statistics. These data were used to estimate the Disability Adjusted Life Years (DALYs) due to cystic echinococcosis (CE) and alveolar echinococcosis (AE). The distribution of DALYs was presented geographically and economically. The echinococcosis DALYs in the Tibetan communities were estimated to be 126,159 (95%UI 122,415-137,675) annually using the method recommended by WHO. AE DALYs were estimated to be 105,829 (95%UI 101,969-117,090), which were more than CE DALYs of 20,330 (95%UI 19,690-21,581). Echinococcosis affects people more in underdeveloped areas. There was a tendency that a higher echinococcosis DALYs were usually correlated a higher altitude. Health services are also poorly provided in terms of number of health staff of 5.05 per 1000 population in comparison with the national average of 5.8 per 1000 population. The data suggest that the echinococcosis burden in the center region of Qinghai-Tibet plateau is higher than that of other regions, and consequently more control and health services should be provided to the region.

摘要

包虫病被世界卫生组织(WHO)视为全球被忽视的人畜共患疾病。就在 20 年前,一些藏区被发现是包虫病的高度流行区。直到最近,我们才能够在 2012 年至 2016 年全国调查提供流行数据后,了解藏区包虫病的总体疾病负担。我们从 2016 年至 2018 年的 9 篇关于包虫病流行率的出版物、151 个藏区县的 10 个包虫病流行率数据库以及 44 个地方统计局、省、州和县级政府网站的人口、国内生产总值(GDP)和卫生人员统计数据以及 2 本省级年度统计数据中提取了数据。这些数据用于估计囊性包虫病(CE)和泡型包虫病(AE)所致残疾调整生命年(DALYs)。DALY 的分布在地理和经济上进行了呈现。使用 WHO 推荐的方法,估计藏区包虫病的 DALY 每年为 126159(95%UI 122415-137675)。AE 的 DALY 估计为 105829(95%UI 101969-117090),高于 CE 的 20330(95%UI 19690-21581)。包虫病在欠发达地区对人们的影响更大。通常,DALY 越高的地区,海拔也越高。与全国每 1000 人 5.8 名卫生人员的平均水平相比,藏区每 1000 人 5.05 名卫生人员的卫生服务也很差。数据表明,青藏高原中心地区的包虫病负担高于其他地区,因此该地区应提供更多的控制和卫生服务。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索