Dmochowski Jakub M, Royal Jeremy T, Lourie Gary M
Department of Orthopedic Surgery, WellStar Atlanta Medical Center, Atlanta, Georgia.
Northside Radiology Associates, Atlanta, Georgia.
J Wrist Surg. 2019 Dec;8(6):503-507. doi: 10.1055/s-0039-1677742. Epub 2019 Feb 1.
With the growing use of metallic implants, increased research has focused on metal hypersensitivity. The purpose of this case report is to describe a patient with a suspected metal allergy to a titanium plate and to review the literature behind this controversial topic. A 45-year-old woman underwent ulnar shortening osteotomy for ulnocarpal abutment. One year later, the patient continued to have chronic pain at the site of the implant, with negative work-up for infection, hardware loosening, or failure. During hardware removal, intraoperative findings revealed titanium particle wear in the surrounding tissues, and subsequent allergy testing revealed a new diagnosis of nickel allergy. Following hardware removal, the patient had complete resolution of her symptoms at 3 months without any recurrence after 12 months from the date of surgery. Metals are the most common cause of allergic contact dermatitis. With the increased use of metallic implants, it is no surprise that metal implant allergies have become a cause for concern. While there are multiple tests to try and diagnose a metal implant allergy, there is no gold standard, and results are often difficult to interpret. Physicians need to be cognizant of metal allergies with there often vague symptoms as we continue to search for more reliable and affordable testing. Metal implant allergies can be difficult to diagnose. It is often a diagnosis of exclusion but requires a heightened sense of awareness in the face of a negative work-up with persistent symptoms.
随着金属植入物使用的增加,越来越多的研究聚焦于金属过敏。本病例报告的目的是描述一名疑似对钛板金属过敏的患者,并回顾这一有争议话题背后的文献。
一名45岁女性因尺腕撞击综合征接受了尺骨短缩截骨术。一年后,患者植入部位持续存在慢性疼痛,感染、内固定松动或失效的检查结果均为阴性。在取出内固定时,术中发现周围组织有钛颗粒磨损,随后的过敏测试显示新诊断为镍过敏。取出内固定后,患者在3个月时症状完全缓解,自手术之日起12个月后无任何复发。
金属是过敏性接触性皮炎最常见的病因。随着金属植入物使用的增加,金属植入物过敏成为一个令人担忧的原因也就不足为奇了。虽然有多种测试试图诊断金属植入物过敏,但没有金标准,结果往往难以解释。在我们继续寻找更可靠且经济实惠的测试方法时,医生需要认识到金属过敏往往症状模糊。
金属植入物过敏可能难以诊断。它通常是一种排除性诊断,但在检查结果为阴性而症状持续存在的情况下,需要提高警惕。