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连续男性患者因憩室病行腹腔镜乙状结肠切除术伴肠系膜下动脉高位结扎的功能结局的前瞻性评估。

Prospective evaluation of functional outcomes after laparoscopic sigmoidectomy with high tie of the inferior mesenteric artery for diverticular disease in consecutive male patients.

机构信息

Department of Colorectal Surgery, Grenoble Alpes University Hospital, CS 10217, 38043, Grenoble Cedex, France.

University Grenoble Alpes, UMR 5525, CNRS, TIMC-IMAG, 38000, Grenoble, France.

出版信息

Tech Coloproctol. 2020 Jan;24(1):33-40. doi: 10.1007/s10151-019-02123-6. Epub 2019 Dec 9.

Abstract

BACKGROUND

To date, there has been no consensus concerning the vascular approach during sigmoid colectomy for diverticular disease. The aim of this study was to determine the functional impact of elective laparoscopic sigmoidectomy performed with high ligation of the inferior mesenteric artery for diverticulitis in consecutive male patients.

METHODS

Twenty-five consecutive patients of median age 53 years were enrolled in a prospective single-centre pilot study at a tertiary teaching hospital. Main outcome measures were functional results. Patients were asked to complete standardized, validated questionnaires to evaluate preoperative and 6 months postoperative bowel symptomatology (Jorge-Wexner Incontinence Score and KESS score), urinary function (IPSS), and sexual function (IIEF). Secondary outcomes were surgical data, morbidity, and quality of life (SF-36).

RESULTS

There were no significant differences between preoperative and 6 months postoperative total scores for bowel symptomatology, urinary function, and sexual function. There were no perioperative deaths. The morbidity rate was 12% including three minor and no major events. Quality of life demonstrated statistically better general health (p < 0.01) and better medical status over the prior 4 weeks at 6 months after surgery, compared to baseline. This single-centre prospective study has a limited number of patients, relatively short follow-up time, and includes only male patients.

CONCLUSION

Laparoscopic sigmoidectomy with high tie of the inferior mesenteric artery for diverticular disease does not induce functional disorders at 6 months after surgery. The benefit of the operation for quality of life is even greater for general health and medical status.

摘要

背景

迄今为止,对于憩室病的乙状结肠切除术的血管入路,尚无共识。本研究旨在确定对连续男性憩室炎患者行选择性腹腔镜乙状结肠切除术并结扎肠系膜下动脉对其功能的影响。

方法

在一家三级教学医院的前瞻性单中心试点研究中,纳入了 25 名中位年龄为 53 岁的连续患者。主要观察指标为功能结果。患者需要完成标准化、验证的问卷,以评估术前和术后 6 个月的肠道症状(Jorge-Wexner 失禁评分和 KESS 评分)、尿功能(IPSS)和性功能(IIEF)。次要结果为手术数据、发病率和生活质量(SF-36)。

结果

肠道症状、尿功能和性功能的总评分在术前和术后 6 个月之间无显著差异。无围手术期死亡。发病率为 12%,包括 3 例轻微事件,无重大事件。与基线相比,生活质量在术后 6 个月时显示出更好的一般健康状况(p<0.01)和过去 4 周的医疗状况。这项单中心前瞻性研究的患者数量有限,随访时间相对较短,且仅包括男性患者。

结论

对于憩室病,腹腔镜乙状结肠切除术并结扎肠系膜下动脉不会在术后 6 个月引起功能障碍。对于生活质量,手术的益处在一般健康和医疗状况方面更大。

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