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青少年胃束带术:一项长达 5 年的纵向研究。

Adolescent Gastric Banding: a 5-Year Longitudinal Study.

机构信息

Division of Pediatric Surgery, Morgan Stanley Children's Hospital of New York Presbyterian/Columbia University Irving Medical Center, 3959, Broadway, NY, 10032, USA.

Department of Surgery, Vagellos College of Physicians and Surgeons of Columbia University, 3959, Broadway, NY, 10032, USA.

出版信息

Obes Surg. 2020 Mar;30(3):828-836. doi: 10.1007/s11695-019-04321-5.

Abstract

BACKGROUND

Laparoscopic adjustable gastric banding (LAGB) is used to treat obesity in adults. Less is known about long-term results of the procedure in adolescents.

OBJECTIVES

To evaluate LAGB 5-year outcomes in teenagers with severe obesity.

SETTING

Children's hospital, USA.

METHODS

Adolescents (14-18 years) underwent LAGB in an FDA-approved observational clinical trial. Outcomes including anthropometric measurements, comorbid conditions, complications, and band retention were collected through 60 months.

RESULTS

One hundred thirty-seven subjects underwent LAGB (94 female, 43 male; 43% white, 37% Hispanic, 17% black; 4% other). Mean age and body mass index (BMI) pre-operatively were 17.0 + 1.2 years and 48.3 + 8.2 kg/m, respectively. Comorbidities were present in 71%. Maximum weight loss occurred by 36 months (mean % excess weight loss (EWL) 40.6 + 35.2, mean % excess BMI loss (EBMIL) 41.6 + 34.9) and was maintained through 5 years for most subjects. There were no significant differences in weight loss by gender. Twenty-three (18%) of 127 adolescents reporting at 60 months achieved 50% excess weight loss. Postoperative heartburn and emesis occurred in 70% and 32%, respectively. Complications requiring additional surgery occurred 80 times in 63 patients. Thirty-three (26%) of 127 subjects contacted at 5 years had undergone band removal.

CONCLUSION

In this study, fewer than 20% of adolescents with severe obesity lost > 50% of their excess weight following LAGB. Nearly 50% of patients required additional surgery. With reports of success following sleeve gastrectomy and gastric bypass, we believe that LAGB is not a preferred choice to treat adolescents with obesity.

摘要

背景

腹腔镜可调节胃束带术(LAGB)用于治疗成年人肥胖症。对于青少年患者,人们对该手术的长期效果知之甚少。

目的

评估严重肥胖青少年接受 LAGB 手术后的 5 年结果。

地点

美国儿童医院。

方法

在一项经 FDA 批准的观察性临床试验中,青少年(14-18 岁)接受 LAGB 治疗。通过 60 个月收集包括人体测量学测量、合并症、并发症和束带保留情况等结果。

结果

137 名患者接受了 LAGB 治疗(94 名女性,43 名男性;43%为白人,37%为西班牙裔,17%为黑人,4%为其他族裔)。术前平均年龄和体重指数(BMI)分别为 17.0±1.2 岁和 48.3±8.2kg/m²。71%的患者存在合并症。最大减重发生在 36 个月(平均超重体重减轻百分比(EWL)40.6±35.2,平均超重 BMI 减轻百分比(EBMIL)41.6±34.9),大多数患者在 5 年内保持这一水平。性别之间的减重无显著差异。在报告 60 个月结果的 127 名青少年中,23 名(18%)达到了 50%的超重体重减轻。术后胃灼热和呕吐的发生率分别为 70%和 32%。63 名患者中有 80 次需要额外手术治疗的并发症。在随访 5 年时,127 名患者中有 33 名(26%)已取出束带。

结论

在这项研究中,严重肥胖的青少年接受 LAGB 手术后,体重减轻超过 50%的患者不到 20%。近 50%的患者需要额外手术。鉴于袖状胃切除术和胃旁路术的成功报道,我们认为 LAGB 不是治疗肥胖青少年的首选方法。

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