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是否应在青少年中施行减重手术?

Should bariatric surgery be performed in adolescents?

机构信息

Department of Gastrosurgical ResearchInstitute of Clinical Sciences, Gothenburg University, Gothenburg, Sweden.

Research DepartmentThe Royal College of Surgeons of England, London, UK.

出版信息

Eur J Endocrinol. 2017 Apr;176(4):D1-D15. doi: 10.1530/EJE-16-0906.

Abstract

Adolescent obesity has markedly increased worldwide in both its extent and prevalence in recent decades and obesity prevention strategies are failing. As a result, effective treatment strategies are urgently needed. As behavioral and pharmacological treatment approaches have only moderate effects in severe obesity, bariatric surgery has begun to emerge as a treatment option. In this debate article, we offer arguments opposing and supporting bariatric surgery in the treatment of severe obesity in adolescents. Bariatric surgery has superior therapeutic outcomes with respect to weight loss and resolution of comorbid diseases over other existing treatments. However, long-term outcomes after bariatric surgery in adolescents are only just beginning to emerge. Furthermore, the procedures are generally considered irreversible, apart from gastric banding. Most importantly, not all adolescents seem to benefit greatly from bariatric surgery and we are not yet able to reliably identify those who stand to gain the greatest benefit. The authors agree that adolescent bariatric surgery should be offered exclusively within formal adolescent obesity programs, delivered by specialist multidisciplinary child/adolescent obesity teams, and within specialist centers, in order to optimize outcomes and minimize potential detrimental effects. Patients and their family/carers must be educated regarding the benefits and risks, potential side effects, expected changes in eating behavior and the lifelong requirement for regular medical follow-up after surgery. Before embarking upon a surgical treatment pathway in adolescents with severe obesity, it may also be beneficial to ensure compliance to treatment is demonstrated, in order to minimize the risk of nutritional deficiencies and associated potential complications.

摘要

青少年肥胖症在近几十年来,无论是在其严重程度还是流行程度上,在全球范围内都显著增加,而肥胖预防策略却收效甚微。因此,迫切需要有效的治疗策略。由于行为和药物治疗方法在重度肥胖症中仅具有适度的效果,因此减重手术已开始成为一种治疗选择。在这篇辩论文章中,我们提出了反对和支持减重手术治疗青少年重度肥胖症的论点。与其他现有治疗方法相比,减重手术在减肥和解决合并症方面具有更好的治疗效果。但是,青少年减重手术后的长期结果才刚刚开始出现。此外,除了胃束带术之外,这些手术通常被认为是不可逆的。最重要的是,并非所有青少年似乎都能从减重手术中获得巨大收益,而我们还不能可靠地识别出那些最有可能受益的人。作者们同意,青少年减重手术应仅在正规的青少年肥胖症计划中提供,由专门的多学科儿童/青少年肥胖症团队在专门的中心进行,以优化结果并最大程度地减少潜在的有害影响。必须对患者及其家属/照顾者进行有关收益和风险、潜在副作用、预期饮食行为变化以及手术后定期进行医疗随访的终身要求的教育。在开始对患有严重肥胖症的青少年进行手术治疗之前,确保治疗的依从性也可能是有益的,以最大程度地减少营养缺乏和相关潜在并发症的风险。

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