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鼻窦提升术中新鲜冷冻同种异体骨:组织学和放射学分析

Fresh-frozen homologous bone in sinus lifting: histological and radiological analysis.

作者信息

Albanese Massimo, Zotti Francesca, Lanaro Luca, Trojan Diletta, Paolin Adolfo, Montagner Giulia, Iannielli Angelica, Rodella Luigi F, Nocini Pier F

机构信息

Department of Surgery, Dentistry, Pediatrics and Gynecology, G. B. Rossi Polyclinic, University of Verona, Verona, Italy.

Department of Surgery, Dentistry, Pediatrics and Gynecology, G. B. Rossi Polyclinic, University of Verona, Verona, Italy -

出版信息

Minerva Stomatol. 2019 Oct;68(5):226-235. doi: 10.23736/S0026-4970.19.04192-X.

DOI:10.23736/S0026-4970.19.04192-X
PMID:31822046
Abstract

BACKGROUND

The aim of this study was to evaluate radiological and histological characteristics of fresh-frozen homologous bone as grafting material for maxillary sinus floor augmentation. Radiological, histological and clinical evaluations were made.

METHODS

Twenty-three patients with a 2 mm to 6 mm alveolar ridge height in the posterior maxilla have been enrolled. Unilateral or bilateral sinus floor augmentations were performed with fresh frozen morcelized homologous bone. Together with implant placement, 7 months after surgery, a bone core was harvested for histological analysis. Radiological measurements were obtained by superimposition of CT scans carried out at the surgery time and six months later. A total of 93 implants were positioned.

RESULTS

A mean (±SD) increase in mineralized tissue height of 10.74±2.82 mm was noticed by comparing the CT scans. Histological analysis revealed the presence of newly formed bone in the grafted sites. The follow up period after the prosthetic load ranged from 8 to 31 months. One implant failure occurred.

CONCLUSIONS

Fresh frozen homologous bone seems to have a good healing pattern and to be a successful and steady grafting material for the treatment of maxillary ridge atrophy. It might be considered a valid alternative to autologous bone in sinus floor augmentation procedures.

摘要

背景

本研究的目的是评估新鲜冷冻同种异体骨作为上颌窦底提升植骨材料的放射学和组织学特征。进行了放射学、组织学和临床评估。

方法

纳入23例上颌后牙区牙槽嵴高度为2mm至6mm的患者。采用新鲜冷冻碎块状同种异体骨进行单侧或双侧上颌窦底提升。在种植体植入的同时,术后7个月采集骨芯进行组织学分析。通过叠加手术时和术后6个月进行的CT扫描获得放射学测量数据。共植入93枚种植体。

结果

通过比较CT扫描发现矿化组织高度平均(±标准差)增加了10.74±2.82mm。组织学分析显示移植部位有新形成的骨组织。修复体加载后的随访期为8至31个月。发生了1例种植体失败。

结论

新鲜冷冻同种异体骨似乎具有良好的愈合模式,是治疗上颌骨嵴萎缩的一种成功且稳定的植骨材料。在鼻窦底提升手术中,它可能被认为是自体骨的有效替代物。

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Medicina (Kaunas). 2024 Jan 31;60(2):252. doi: 10.3390/medicina60020252.
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J Funct Biomater. 2023 Jan 29;14(2):76. doi: 10.3390/jfb14020076.
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