Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Kangwon-do, 26493, South Korea.
R&D Center, MEDIANA Co., Ltd., Wonju, Republic of Korea.
J Med Syst. 2019 Dec 10;44(1):18. doi: 10.1007/s10916-019-1514-z.
This study investigates the feasibility of estimation of blood pressure (BP) using a single earlobe photoplethysmography (Ear PPG) during cardiopulmonary resuscitation (CPR). We have designed a system that carries out Ear PPG for estimation of BP. In particular, the BP signals are estimated according to a long short-term memory (LSTM) model using an Ear PPG. To investigate the proposed method, two statistical analyses were conducted for comparison between BP measured by the micromanometer-based gold standard method (BP) and the Ear PPG-based proposed method (BP) for swine cardiac model. First, Pearson's correlation analysis showed high positive correlations (r = 0.92, p < 0.01) between BP and BP. Second, the paired-samples t-test on the BP parameters (systolic and diastolic blood pressure) of the two methods indicated no significant differences (p > 0.05). Therefore, the proposed method has the potential for estimation of BP for CPR biofeedback based on LSTM using a single Ear PPG.
本研究旨在探讨在心肺复苏（CPR）期间使用单个耳垂光体积描记法（Ear PPG）估计血压（BP）的可行性。我们设计了一种系统，该系统可进行 Ear PPG 以估计 BP。具体来说，根据长短期记忆（LSTM）模型使用 Ear PPG 来估计 BP 信号。为了研究该方法，针对猪心脏模型，我们对基于微动脉血压计的金标准方法（BP）和基于 Ear PPG 的提出方法（BP）测量的 BP 进行了两项统计学分析。首先，Pearson 相关分析显示 BP 和 BP 之间存在高度正相关（r=0.92，p<0.01）。其次，两种方法的 BP 参数（收缩压和舒张压）的配对样本 t 检验表明无显著差异（p>0.05）。因此，该方法有可能基于 LSTM 使用单个 Ear PPG 进行 CPR 生物反馈的 BP 估计。
