Arana G W, Epstein S, Molloy M, Greenblatt D J
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425.
J Clin Psychiatry. 1988 Nov;49(11):448-9.
A patient with atypical bipolar disorder and panic attacks treated with alprazolam 7.5 mg/day showed a greater than 50% reduction in plasma alprazolam concentrations after carbamazepine treatment was initiated and experienced a corresponding clinical deterioration. Clinical and plasma concentration data are presented.
一名患有非典型双相情感障碍和惊恐发作的患者，每天服用7.5毫克阿普唑仑进行治疗，在开始使用卡马西平治疗后，血浆阿普唑仑浓度降低了50%以上，并出现了相应的临床病情恶化。文中呈现了临床和血浆浓度数据。
