神经生长因子（NGF）与血管内皮生长因子（VEGF）在健康个体中的相互作用。
: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals.
机构信息
Department of Psychiatry, Social Psychiatry and Psychotherapy, Center for Addiction Research, Medical School Hanover, Germany.
Celerion Switzerland AG, Switzerland.
出版信息
Dis Markers. 2019 Nov 11;2019:7510315. doi: 10.1155/2019/7510315. eCollection 2019.
NGF and VEGF are known to be involved in different psychiatric diseases. In order to verify hints from basic research that both neurotrophines interact with each other, serum levels of NGF and VEGF were measured in a cohort of 33 healthy individuals and correlated. NGF level was 126.30 pg/mL (±155.43), and VEGF level was 57.28 pg/mL (±44.48). Both factors were significantly correlated, confirming their interaction and legitimising the usage of their respective ratio (0.8 (±0.42)) as a less varying additional marker in prospective studies.
神经生长因子（NGF）和血管内皮生长因子（VEGF）已知与不同的精神疾病有关。为了验证基础研究中提示的两种神经营养因子相互作用的线索，我们测量了 33 名健康个体的血清 NGF 和 VEGF 水平并进行了相关性分析。NGF 水平为 126.30 pg/mL（±155.43），VEGF 水平为 57.28 pg/mL（±44.48）。这两种因子均呈显著相关性，证实了它们的相互作用，并使各自比值（0.8（±0.42））作为一个变化较小的附加标志物在前瞻性研究中的使用合法化。
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