Degheili Jad A, El-Asmar Jose M, Moussally Moustafa, Abou Heidar Nassib, El Hajj Albert
Division of Urology, Department of Surgery, American University of Beirut Medical Center, Beirut, LBN.
Cureus. 2019 Nov 3;11(11):e6066. doi: 10.7759/cureus.6066.
Human schistosomiasis or bilharzia is a parasitic disease that highly impacts a country's health and economic systems specifically when it affects individuals residing in underdeveloped countries. Daughter eggs produced by colonized Schistosoma can lead to multisystem immune-mediated response, one of them is an intravesicular granulomatous reaction leading to intramural lesions. Such outcome is directly related to the incubation of adult worms within the perivesical urogenital venous plexus. We hereby report an incidental discovery of calcified bladder wall lesions in a female patient residing in the United States for the last 27 years who presented with lower urinary tract symptoms. Despite a negative past medical history of schistosomiasis, intraoperative biopsies confirmed the presence of a calcified Schistosoma haematobium ova. Following that, a brief literature review of the pathogenesis and urogenital manifestations of Schistosoma is highlighted.
人类血吸虫病或裂体吸虫病是一种寄生虫病,对一个国家的卫生和经济系统有重大影响,特别是当它影响到生活在不发达国家的个人时。被殖民的血吸虫产生的子卵可导致多系统免疫介导反应,其中之一是膀胱内肉芽肿反应,导致壁内病变。这种结果与成虫在膀胱周围泌尿生殖静脉丛中的孵化直接相关。我们在此报告,一名在美国居住了27年的女性患者出现下尿路症状,偶然发现膀胱壁钙化病变。尽管过去血吸虫病病史呈阴性,但术中活检证实存在钙化的埃及血吸虫卵。在此之后,重点对血吸虫的发病机制和泌尿生殖系统表现进行了简要的文献综述。