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[关于整形、重建和美容手术中抗生素预防的指南提案]

[Proposal of guidelines for antibiotic prophylaxis in plastic, reconstructive, and aesthetic surgery].

作者信息

Ramon A, Correia N, Smati M, Malinovsky J M, Bajolet O, Reynaud J P, Perrot P, Bodin F, Francois C

机构信息

Chirurgie plastique, reconstructrice et esthétique, hôpital maison Blanche, CHU Reims, 45, rue Cognacq Jay, 51100 Reims, France.

Anesthésie et réanimation, hôpital Maison Blanche, CHU Reims, 45, rue Cognacq Jay, 51100 Reims, France.

出版信息

Ann Chir Plast Esthet. 2020 Feb;65(1):13-23. doi: 10.1016/j.anplas.2019.10.001. Epub 2019 Dec 9.

DOI:10.1016/j.anplas.2019.10.001
PMID:31831208
Abstract

BACKGROUND

In plastic surgery, guidelines about antibiotic prophylaxis are inaccurate and incomplete, due to result the absence of high-level studies on this subject. The main aim is to establish national common recommendations for plastic surgery antibiotic prophylaxis.

MATERIALS AND METHODS

A working group will discuss and validate a multi-center analysis of practices in three University Hospital Centers compared to an interdisciplinary analysis of recommendations to the French Society of Anaesthesia and Intensive Care Medicine and scientific literature. This working group is composed of plastic surgeon members of the French Society of Aesthetic Reconstructive Plastic Surgery, infectious disease physicians, and anaesthesiologists to define clear and precise antibiotic prophylaxis recommendations.

RESULTS

Antibiotic prophylaxis with cefazoline (or clindamycine±gentamicine in case of allergy), has been recommended for general surgery with flap or implants, for breast surgery, lipofilling, and rhinoplasty. In other plastic surgery, no antibiotic prophylaxis has been recommended.

CONCLUSION

We established common recommendations for plastic surgery antibiotic prophylaxis that is the first step to update these recommendations. Now, they can be evaluated in clinical situation to validate them.

摘要

背景

在整形手术中,由于缺乏关于该主题的高水平研究,抗生素预防的指南不准确且不完整。主要目的是制定整形手术抗生素预防的国家通用建议。

材料与方法

一个工作组将讨论并验证对三个大学医院中心实践的多中心分析,并与法国麻醉与重症医学学会的建议跨学科分析以及科学文献进行比较。该工作组由法国美容重建整形外科学会的整形外科医生成员、传染病医生和麻醉师组成,以确定明确而精确的抗生素预防建议。

结果

对于带皮瓣或植入物的普通外科手术、乳房手术、脂肪填充和隆鼻手术,建议使用头孢唑林进行抗生素预防(过敏时用克林霉素±庆大霉素)。在其他整形手术中,不建议进行抗生素预防。

结论

我们制定了整形手术抗生素预防的通用建议,这是更新这些建议的第一步。现在,可以在临床情况下对其进行评估以验证它们。

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[Proposal of guidelines for antibiotic prophylaxis in plastic, reconstructive, and aesthetic surgery].[关于整形、重建和美容手术中抗生素预防的指南提案]
Ann Chir Plast Esthet. 2020 Feb;65(1):13-23. doi: 10.1016/j.anplas.2019.10.001. Epub 2019 Dec 9.
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Antibiotic prophylaxis in clean and clean-contaminated plastic surgery: A critical review.清洁和清洁污染整形手术中的抗生素预防:批判性评价。
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Perioperative antibiotic prophylaxis in plastic surgery: a prospective study of 1,100 adult patients.整形外科学围手术期抗生素预防:1100 例成年患者的前瞻性研究。
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[Guidelines for antibiotic prophylaxis in plastic, reconstructive, and aesthetic surgery].[整形、重建和美容手术中抗生素预防应用指南]
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Efficacy and safety profile of antibiotic prophylaxis usage in clean and clean-contaminated plastic and reconstructive surgery: a meta-analysis of randomized controlled trials.清洁及清洁-污染的整形与重建手术中抗生素预防性使用的疗效与安全性概况:一项随机对照试验的荟萃分析
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