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抗生素预防的当前处方趋势:一项美容整形手术的多国调查。

Current prescription trends in antibiotic prophylaxis: a multinational survey in esthetic plastic surgery.

作者信息

Perez Pachon Mauricio E, Hoyos Alfredo E, Luna-Pisciotti Tatiana, Benavides Jorge E, Garcia Danna, Boras Osorio Mariana

机构信息

Scientific Department at Total Definer Medical, Bogota, COL, Rochester, Minnesota, USA.

Plastic Surgeon, CEO at Total Definer Medical; Member of the Colombian Society of Plastic, Aesthetic, Maxillofacial, and Hand Surgery, Member of the American Society of plastic surgeons (ASPS), Private practice, Bogota, Colombia.

出版信息

Ann Med Surg (Lond). 2025 Apr 10;87(6):3150-3156. doi: 10.1097/MS9.0000000000003274. eCollection 2025 Jun.

Abstract

BACKGROUND

Surgical site infections pose a significant challenge in esthetic surgery, representing one of the most prevalent complications. While research in plastic surgery remains limited, reported rates of SSI range from 0.5% to 32.6%. Although the overall incidence of infections in most esthetic surgeries is low, it carries a significant burden of morbidity, hospital readmissions, and prolonged hospital stays.

PURPOSE

Our study aims to provide evidence-based recommendations regarding the prescription of prophylactic antibiotics for the most common esthetic plastic surgery procedures, based on current trends among plastic surgeons.

METHODS

An anonymous online survey was conducted among board-certified plastic surgeons to assess antibiotic prophylaxis practices. The survey was distributed via individual links on social media, plastic surgery society platforms, and private surgeon groups. Responses were recorded between February and April 2022 and were available in three different languages: English, Portuguese, and Spanish. The questionnaire covered eight common esthetic procedures, evaluating antibiotic use (prophylactic and non-prophylactic), duration, and type prescribed.

RESULTS

Our study analyzed data from 2216 plastic surgery procedures, with 277 respondents answering each of the three questions per procedure. Cephalosporins were the most commonly prescribed antibiotics (73.3%), followed by quinolones (12.9%). Antibiotic therapy exceeded 5 days in 39.6% of cases, while 32.3% reported a 5-day duration. Single-dose prophylaxis was used in only 12% of cases.

CONCLUSION

The rise of multidrug-resistant microorganisms is a growing global concern. Despite established guidelines on antibiotic prophylaxis, misuse among surgeons persists. Our findings highlight the urgent need for stricter antimicrobial stewardship, ensuring that antibiotics are prescribed only when clinically indicated.

LEVEL OF EVIDENCE

III. Type of Study: Cross-Sectional, Observational Survey Study.

摘要

背景

手术部位感染在美容手术中构成重大挑战,是最常见的并发症之一。虽然整形手术方面的研究仍然有限,但报告的手术部位感染率在0.5%至32.6%之间。尽管大多数美容手术中感染的总体发生率较低,但它带来了相当大的发病负担、医院再入院率和延长的住院时间。

目的

我们的研究旨在根据整形外科医生的当前趋势,为最常见的美容整形手术预防性抗生素的处方提供循证建议。

方法

对获得委员会认证的整形外科医生进行了一项匿名在线调查,以评估抗生素预防措施的实施情况。该调查通过社交媒体、整形外科学会平台和私人外科医生团体上的个人链接进行分发。在2022年2月至4月期间记录回复,提供英语、葡萄牙语和西班牙语三种不同语言版本。问卷涵盖八种常见的美容手术,评估抗生素的使用(预防性和非预防性)、持续时间和处方类型。

结果

我们的研究分析了2216例整形手术的数据,每个手术有277名受访者回答了三个问题中的每一个。头孢菌素是最常用的抗生素(73.3%),其次是喹诺酮类(12.9%)。39.6%的病例抗生素治疗超过5天,而32.3%的病例报告持续时间为5天。仅12%的病例使用单剂量预防。

结论

多重耐药微生物的出现是全球日益关注的问题。尽管有关于抗生素预防的既定指南,但外科医生中仍存在滥用现象。我们的研究结果凸显了迫切需要更严格的抗菌管理,确保仅在临床指征明确时才开具抗生素处方。

证据水平

III。研究类型:横断面观察性调查研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1006/12140726/21b19a3039a2/ms9-87-3150-g001.jpg

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