微囊性附属器癌：一例显示小汗腺导管分化的病例。

Microcystic adnexal carcinoma: a case showing eccrine duct differentiation.

作者信息

Ceballos P I, Penneys N S, Cohen B H

机构信息

Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Florida.

出版信息

J Dermatol Surg Oncol. 1988 Nov;14(11):1236-9. doi: 10.1111/j.1524-4725.1988.tb03480.x.

DOI:10.1111/j.1524-4725.1988.tb03480.x

PMID:3183176

Abstract

Microcystic adnexal carcinoma (MAC) is a cutaneous neoplasm comprised of pilar and sweat duct structures. Characteristically, the ductal structures manifest immunoreactivity for carcinoembryonic antigen (CEA) on immunostaining. The case of MAC discussed here shows strictly sweat duct differentiation. Using a monoclonal antibody to salivary mucin (CF-1) that is specific for eccrine duct, we identify the neoplastic structures to be of eccrine sweat duct histogenesis.

摘要

微囊性附属器癌（MAC）是一种由毛囊和汗腺导管结构组成的皮肤肿瘤。其特征性表现为，在免疫染色时，导管结构对癌胚抗原（CEA）呈免疫反应性。本文所讨论的MAC病例显示为严格的汗腺导管分化。使用针对小汗腺导管特异性的唾液粘蛋白单克隆抗体（CF-1），我们确定肿瘤结构来源于小汗腺导管。