以胃溃疡为表现的HIV相关卡波西肉瘤及经高效抗逆转录病毒治疗后的缓解
Gastric Ulcer as Presentation of HIV-Associated Kaposi Sarcoma and Resolution With HAART Therapy.
作者信息
Nassri Rama, Muftah Abdullah, Muftah Mayssan, Nassri Ammar, Alkhasawneh Ahmad
机构信息
Alfaisal University College of Medicine, Riyadh, KSA.
USF Morsani College of Medicine, Tampa, FL.
出版信息
ACG Case Rep J. 2019 Oct 28;6(10):e00262. doi: 10.14309/crj.0000000000000262. eCollection 2019 Oct.
Abstract
Kaposi sarcoma (KS) is a neoplasm of endothelium-derived cells that are associated with human herpesvirus 8 infection. In the setting of HIV, extensive disease typically necessitates highly active antiretroviral therapy in conjunction with chemotherapy. We report a patient who presented with gastrointestinal symptoms and was found to have KS presenting only as cratered gastric ulcers. The patient declined chemotherapy and was treated with highly active antiretroviral therapy alone and had complete resolution of KS on endoscopy and imaging up to 3 years later.
摘要
卡波西肉瘤（KS）是一种与人类疱疹病毒8感染相关的内皮细胞来源的肿瘤。在艾滋病病毒感染的情况下，广泛的病变通常需要高效抗逆转录病毒疗法联合化疗。我们报告了一名出现胃肠道症状的患者，该患者被发现患有仅表现为凹陷性胃溃疡的卡波西肉瘤。患者拒绝化疗，仅接受高效抗逆转录病毒疗法治疗，直至3年后内镜检查和影像学检查显示卡波西肉瘤完全消退。
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