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肺炎或卡波西肉瘤:隐匿于不依从治疗的HIV患者呼吸困难背后的疾病

Pneumonia or Kaposi Sarcoma: Beneath the Dyspnea With Non-compliance of HIV.

作者信息

Roy Pooja, Parisapogu Anusha, Agrawal Harshita

机构信息

Internal Medicine, Harlem Hospital Center, New York, USA.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA.

出版信息

Cureus. 2022 Oct 10;14(10):e30152. doi: 10.7759/cureus.30152. eCollection 2022 Oct.

Abstract

Human herpesvirus 8 (HHV-8) or Kaposi sarcoma herpesvirus is the cause of Kaposi sarcoma (KS), the most prevalent cancer related to acquired immune deficiency syndrome. About 90% of the time, KS is accompanied by cutaneous lesions; however, systemic illness can develop without cutaneous involvement. Today's highly active antiretroviral therapy (HAART) era has seen a decrease in the prevalence of KS. In immunocompromised individuals, it may be challenging to differentiate between pneumonia and the clinical characteristics of pulmonary KS, which might make diagnosis more challenging. HAART is the first-line therapy for KS, and its usage has reduced the incidence of KS. Depending on how severe the illness is, systemic chemotherapy could be helpful. We report the case of a young man who presented with pulmonary symptoms in the presence of a pharyngeal mass and was later found to have bilateral pulmonary metastasis. Interestingly, this diagnosis was made in the absence of classic cutaneous lesions. The patient was counseled for quality of life with medication and intervention compliance, and a consultation with an oncologist was set up.

摘要

人类疱疹病毒8型(HHV-8)或卡波西肉瘤疱疹病毒是卡波西肉瘤(KS)的病因,卡波西肉瘤是与获得性免疫缺陷综合征相关的最常见癌症。约90%的情况下,KS伴有皮肤病变;然而,也可能在无皮肤受累的情况下出现全身性疾病。在当今高效抗逆转录病毒疗法(HAART)时代,KS的患病率有所下降。在免疫功能低下的个体中,区分肺炎和肺KS的临床特征可能具有挑战性,这可能使诊断更具挑战性。HAART是KS的一线治疗方法,其使用降低了KS的发病率。根据病情严重程度,全身化疗可能会有帮助。我们报告了一名年轻男性的病例,该患者出现肺部症状并伴有咽部肿块,后来发现有双侧肺转移。有趣的是,该诊断是在没有典型皮肤病变的情况下做出的。对患者进行了关于药物治疗和干预依从性的生活质量咨询,并安排了与肿瘤学家的会诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61d2/9646360/fb0e85c873b3/cureus-0014-00000030152-i01.jpg

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