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丧偶后患髋部骨折风险增加——丧亲脆弱性得到进一步支持?

Increased risk for hip fracture after death of a spouse-further support for bereavement frailty?

机构信息

Geriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, 413 45, Göteborg, Sweden.

Region Västra Götaland, Geriatric Medicine Clinic, Sahlgrenska University Hospital, 431 80, Mölndal, Sweden.

出版信息

Osteoporos Int. 2020 Mar;31(3):485-492. doi: 10.1007/s00198-019-05242-w. Epub 2019 Dec 12.

DOI:10.1007/s00198-019-05242-w
PMID:31832693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7075824/
Abstract

UNLABELLED

Death of a spouse is associated with poorer physical and mental health. We followed all married individuals, born from 1902 to 1942, during the period from 1987 to 2002, and found that widows and widowers had higher risk for hip fracture, compared with still married women and men.

INTRODUCTION

Spousal bereavement can lead to poorer physical and mental health. We aimed to determine whether married women and men had an elevated risk of hip fracture after death of a spouse.

METHODS

In a retrospective cohort study, we followed all Swedish married individuals aged 60 to 100 years (n = 1,783,035), from 1987 to 2002. Data are presented as mean with 95% confidence interval (CI).

RESULTS

During the follow-up period, 21,305 hip fractures among widows and 6538 hip fractures among widowers were noted. The hazard ratio (HR) for hip fracture in widows compared with married women was 1.34 (95% CI 1.31 to 1.37) and for widowers compared with married men 1.32 (95% CI 1.29 to 1.35). The HR for hip fracture in the first 6 months after death of a spouse was in widows compared with married women 1.62 (95% CI 1.53 to 1.71) and in widowers compared with married men 1.84 (95% CI 1.68 to 2.03). The elevated risk was especially prominent in young widowers in the age range 60-69 years. During the first 6 months they showed a HR of 2.76 (95% CI 1.66 to 4.58) for a hip fractvure compared with age matched married men. Widows aged 60-69 years showed a HR of 1.59 (95% CI 1.26 to 1.99) compared with age matched married women.

CONCLUSION

Our observation of a higher hip fracture risk in both genders in connection with the death of a spouse indicates a possible effect of bereavement on frailty.

摘要

目的

丧偶与较差的身心健康相关。本研究旨在确定配偶去世后,已婚女性和男性髋部骨折的风险是否增加。

方法

在一项回顾性队列研究中,我们随访了 1987 年至 2002 年期间所有年龄在 60 至 100 岁的瑞典已婚个体(n=1783035)。数据以平均值和 95%置信区间(CI)表示。

结果

在随访期间,观察到 21305 例寡妇髋部骨折和 6538 例鳏夫髋部骨折。与已婚女性相比,寡妇髋部骨折的风险比(HR)为 1.34(95%CI 1.31 至 1.37),鳏夫为 1.32(95%CI 1.29 至 1.35)。配偶去世后 6 个月内,与已婚女性相比,寡妇髋部骨折的 HR 为 1.62(95%CI 1.53 至 1.71),鳏夫为 1.84(95%CI 1.68 至 2.03)。这种风险在年龄在 60-69 岁的年轻鳏夫中尤为明显。在最初的 6 个月内,他们髋部骨折的 HR 为 2.76(95%CI 1.66 至 4.58),与年龄匹配的已婚男性相比。60-69 岁的寡妇与年龄匹配的已婚女性相比,HR 为 1.59(95%CI 1.26 至 1.99)。

结论

我们观察到配偶死亡后,两性髋部骨折风险均升高,这表明丧偶可能对脆弱性有影响。

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