Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, P. R. China.
College of Life Science and Technology, Gansu Agricultural University, Lanzhou 730070, P. R. China.
Plant Cell Physiol. 2020 Feb 1;61(2):225-242. doi: 10.1093/pcp/pcz230.
Reversible protein phosphorylation orchestrated by protein kinases and phosphatases is a major regulatory event in plants and animals. The SnRK2 subfamily consists of plant-specific protein kinases in the Ser/Thr protein kinase superfamily. Early observations indicated that SnRK2s are mainly involved in response to abiotic stress. Recent evidence shows that SnRK2s are multifarious players in a variety of biological processes. Here, we summarize the considerable knowledge of SnRK2s, including evolution, classification, biological functions and regulatory mechanisms at the epigenetic, post-transcriptional and post-translation levels.
由蛋白激酶和磷酸酶协调的可逆蛋白质磷酸化是动植物的主要调节事件。SnRK2 亚家族由丝氨酸/苏氨酸蛋白激酶超家族中的植物特异性蛋白激酶组成。早期的观察表明,SnRK2s 主要参与非生物胁迫的响应。最近的证据表明,SnRK2s 是多种生物学过程中的多功能参与者。在这里,我们总结了 SnRK2s 的大量知识,包括进化、分类、生物功能以及在表观遗传、转录后和翻译后水平的调控机制。