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“如果第一次不成功”:在患有室上性心动过速的年轻患者中重复消融。

"If at first you don't succeed": repeat ablations in young patients with supraventricular tachycardia.

机构信息

Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital at Montefiore Medical Center, Albert Einstein College of Medicine, 3415 Bainbridge Ave, Bronx, NY, 10467, USA.

Division of Cardiology, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 34th & Civic Center Boulevard, Philadelphia, PA, 19104, USA.

出版信息

J Interv Card Electrophysiol. 2020 Nov;59(2):423-429. doi: 10.1007/s10840-019-00672-2. Epub 2019 Dec 13.

Abstract

PURPOSE

Success rates for catheter ablation of supraventricular tachycardia (SVT) in the young exceed 90%. While studies have described reasons for initial ablation failure, less is known about outcomes of repeat ablation attempts. The purpose of this study was to report acute and mid-term success rates for second ablation attempts in young patients, as well as to analyze factors that may affect these outcomes.

METHODS

Retrospective single-center study of all patients undergoing a second ablation attempt for WPW (Wolff-Parkinson-White) or SVT from 2008 to 2017. Inclusion criteria are all patients < 21 years old at the time of their first ablation who underwent a second ablation attempt. An intention to treat analysis was performed.

RESULTS

Fifty-five patients met inclusion criteria, with a median age of 15 years (IQR 12-16). The most common arrhythmia mechanisms at repeat procedure were single accessory pathways (n = 32, 58%) and AVNRT (n = 14, 25%). Six patients (11%) were found to have a different SVT mechanism than at initial ablation. Acute success at repeat ablation was achieved in 48 patients (87%). At mid-term follow-up (10.5 months, IQR 0.6-25), four patients (8% of acute successes) experienced SVT recurrence. The overall success rate of repeat ablations, accounting for acute and mid-term failures, was 80%.

CONCLUSIONS

In this report of 55 young patients who underwent repeat ablation for WPW and/or SVT, acute and mid-term success rates were 87% and 80%, respectively. These data may help inform decision-making when caring for patients with persistent or recurrent SVT after an initial ablation attempt.

摘要

目的

导管消融术治疗室上性心动过速(SVT)的成功率在年轻人中超过 90%。虽然已有研究描述了初始消融失败的原因,但对于重复消融尝试的结果了解较少。本研究旨在报告年轻患者行第二次消融尝试的即刻和中期成功率,并分析可能影响这些结果的因素。

方法

回顾性分析 2008 年至 2017 年间所有因 WPW(Wolff-Parkinson-White)或 SVT 行第二次消融的年轻患者(<21 岁)。纳入标准为所有患者均在第一次消融时<21 岁,且行第二次消融。进行意向性治疗分析。

结果

55 例患者符合纳入标准,中位年龄为 15 岁(IQR 12-16)。第二次消融时最常见的心律失常机制是单个附加旁路(n=32,58%)和房室结折返性心动过速(AVNRT,n=14,25%)。6 例患者(11%)的SVT机制与初次消融时不同。48 例(87%)患者在第二次消融即刻成功。在中期随访(10.5 个月,IQR 0.6-25)中,4 例(急性成功患者的 8%)出现 SVT 复发。考虑到急性和中期失败,重复消融的总成功率为 80%。

结论

在这项对 55 例因 WPW 和/或 SVT 行重复消融的年轻患者的报告中,即刻和中期成功率分别为 87%和 80%。这些数据可能有助于在为初次消融尝试后持续性或复发性 SVT 患者提供护理时做出决策。

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