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随访无预激综合征的儿童或青少年阵发性室上性心动过速。

Follow-up of children or teenagers with paroxysmal supraventricular tachycardia, but without pre-excitation syndrome.

机构信息

Adult and Paediatric Cardiology, CHU de Brabois, 42 bis, rue du Colonel-Driant, 54220 Malzéville, France.

Adult and Paediatric Cardiology, CHU de Brabois, 42 bis, rue du Colonel-Driant, 54220 Malzéville, France.

出版信息

Arch Cardiovasc Dis. 2017 Nov;110(11):599-606. doi: 10.1016/j.acvd.2017.01.013. Epub 2017 Jul 24.

Abstract

BACKGROUND

Paroxysmal supraventricular tachycardia (SVT) is considered benign in children if the electrocardiogram in sinus rhythm is normal, but causes anxiety in parents, children and doctors.

AIMS

To report on the clinical and electrophysiological data from children with SVT, their follow-up and management.

METHODS

Overall, 188 children/teenagers (mean age 15±2.8 years) with a normal electrocardiogram in sinus rhythm were studied for SVT, and followed for 2.3±4 years.

RESULTS

SVT was poorly tolerated in 30/188 children (16.0%). SVT was related to atrioventricular nodal reentrant tachycardia (AVNRT) (n=133) or atrioventricular reentrant tachycardia (AVRT) over a concealed accessory pathway (n=55; 29.3%). Ablation of the slow pathway (n=66) or the accessory pathway (n=43) was performed without general anaesthesia, 2±3 years after initial evaluation. Failure or refusal to continue occurred in 18/109 (16.5%) children: 7/66 with AVNRT (10.6%), 11/43 with AVRT (25.6%) (P<0.001). Symptoms of SVT recurred in 20/91 children (22.0%) with apparently successful ablation: 6/91 (6.6%) had real SVT recurrence; 14/91 (15.4%) had only a sinus tachycardia, more frequent in AVNRT (11/59; 18.6%) than AVRT (3/32; 9.4%) (P<0.05). In 13 children treated with an antiarrhythmic drug (AAD), SVT recurred in four; two presented AAD-related syncope. In 66 untreated children, one death was noted after excessive AAD infusion to stop SVT; the others remained asymptomatic or had well-tolerated SVT.

CONCLUSIONS

At the time of ablation, SVT management remains difficult in children. Indications for ablation are more common in AVRT than in AVNRT, but failures are frequent; 22.0% remained symptomatic after successful ablation, but false recurrences were frequent (15.4%). Without ablation, one third had a spontaneous favourable evolution.

摘要

背景

如果阵发性室上性心动过速(SVT)患儿窦性心律心电图正常,则被认为是良性的,但会引起家长、儿童和医生的焦虑。

目的

报告 SVT 患儿的临床和电生理数据、随访和管理情况。

方法

共有 188 名(平均年龄 15±2.8 岁)窦性心律心电图正常的 SVT 患儿接受了研究,并随访 2.3±4 年。

结果

30/188 名(16.0%)患儿 SVT 症状耐受性差。SVT 与房室结折返性心动过速(AVNRT)(n=133)或隐匿性旁路参与的房室折返性心动过速(AVRT)(n=55;29.3%)有关。在初次评估后 2±3 年,无需全身麻醉即可进行慢径消融(n=66)或旁路消融(n=43)。109 名(16.5%)患儿中有 18 名拒绝或失败继续治疗:66 名 AVNRT 患儿中 7 名(10.6%),43 名 AVRT 患儿中 11 名(25.6%)(P<0.001)。91 名看似消融成功的患儿中有 20 名(22.0%)出现 SVT 症状复发:6/91(6.6%)出现真正的 SVT 复发;14/91(15.4%)仅有窦性心动过速,AVNRT 中更常见(11/59;18.6%),而非 AVRT(3/32;9.4%)(P<0.05)。13 名接受抗心律失常药物(AAD)治疗的患儿中有 4 名出现 SVT 复发,其中 2 名出现 AAD 相关晕厥。在 66 名未接受治疗的患儿中,1 名患儿因过量输注 AAD 以停止 SVT 而死亡,其余患儿无症状或症状可耐受。

结论

在进行消融时,儿童 SVT 的管理仍然具有挑战性。AVRT 患儿消融适应证较 AVNRT 患儿更常见,但消融失败率较高;消融成功后仍有 22.0%患儿出现症状,但复发多为假复发(15.4%)。未行消融治疗的患儿中,有 1/3 出现自发的良好转归。

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