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近期发作的心房颤动患者采用延迟转复心律的方法更好吗?是的。

Is delayed cardioversion the better approach in recent-onset atrial fibrillation? Yes.

机构信息

Department of Electrophysiology and Clinical Arrhythmology, ASST Rhodense, Rho and Garbagnate M.se Hospitals, C.so Europa 250, Rho, 20017, Milan, Italy.

出版信息

Intern Emerg Med. 2020 Jan;15(1):1-4. doi: 10.1007/s11739-019-02225-x. Epub 2019 Dec 13.

DOI:10.1007/s11739-019-02225-x
PMID:31834587
Abstract

Atrial fibrillation is the most common sustained arrhythmia encountered in primary care practice and represents a significant burden on the health care system with a higher than expected hospitalization rate from the emergency department. The first goal of therapy is to assess the patient's symptoms and hemodynamic status. There are multiple acute management strategies for atrial fibrillation including heart rate control, immediate direct-current cardioversion, or pharmacologic cardioversion. Given the variety of approaches to acute atrial fibrillation, it is often difficult to consistently provide cost-effectiveness care. The likelihood of spontaneous conversion of acute atrial fibrillation to sinus rhythm is reported to be really high. Although active cardioversion of recent-onset atrial fibrillation is generally considered to be safe, the question arises of whether the strategy of immediate treatment for a condition that is likely to resolve spontaneously is acceptable for hemodynamically stable patients. Based on published data, non-managed acute treatment of atrial fibrillation appears to be cost-saving. The observation of a patient with recent-onset atrial fibrillation in a dedicated unit within the emergency department reduces the need for acute cardioversion in almost two-thirds of the patients, and reduces the median length of stay, without negatively affecting long-term outcome, thus reducing the related health care costs. However, to let these results broadly applicable, defined treatment algorithms and access to prompt follow-up are needed, which may not be practical in all settings.

摘要

心房颤动是初级保健实践中最常见的持续性心律失常,它给医疗保健系统带来了巨大的负担,其急诊科的住院率高于预期。治疗的首要目标是评估患者的症状和血液动力学状况。心房颤动有多种急性管理策略,包括心率控制、立即直流电复律或药物复律。鉴于急性心房颤动的治疗方法多种多样,因此很难始终如一地提供具有成本效益的护理。据报道,急性心房颤动自发转为窦性心律的可能性非常高。虽然最近发作的心房颤动的主动复律通常被认为是安全的,但对于血液动力学稳定的患者,是否可以接受对可能自发缓解的病症进行即刻治疗的策略,这是一个存在争议的问题。基于已发表的数据,对心房颤动的急性非管理治疗似乎可以节省成本。在急诊科的专门病房中观察到近期发作的心房颤动患者,可使近三分之二的患者无需进行急性复律,并且可以缩短中位住院时间,而不会对长期预后产生负面影响,从而降低相关的医疗保健费用。然而,要使这些结果广泛适用,需要制定明确的治疗算法并能够及时进行随访,但在所有情况下可能都不切实际。

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本文引用的文献

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Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation.近期发作心房颤动的早期或延迟电复律。
N Engl J Med. 2019 Apr 18;380(16):1499-1508. doi: 10.1056/NEJMoa1900353. Epub 2019 Mar 18.
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The RACE to Treat Atrial Fibrillation in the Emergency Department.急诊科治疗心房颤动的竞赛
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对抗新型冠状病毒肺炎的新兴治疗方式
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Managing atrial fibrillation: the need for an individualized approach even in the emergency department.心房颤动的管理:即使在急诊科也需要个性化方法。
Intern Emerg Med. 2020 Jan;15(1):9-12. doi: 10.1007/s11739-019-02260-8. Epub 2019 Dec 21.
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Implementation of an emergency department atrial fibrillation and flutter pathway improves rates of appropriate anticoagulation, reduces length of stay and thirty-day revisit rates for congestive heart failure.实施急诊科心房颤动和心房扑动治疗路径可提高适当抗凝治疗的比例,缩短住院时间,并降低充血性心力衰竭患者30天内的复诊率。
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Outcomes for Emergency Department Patients With Recent-Onset Atrial Fibrillation and Flutter Treated in Canadian Hospitals.加拿大医院对近期发生心房颤动和心房扑动的急诊科患者的治疗结果。
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Acute cardioversion vs a wait-and-see approach for recent-onset symptomatic atrial fibrillation in the emergency department: Rationale and design of the randomized ACWAS trial.急诊科近期发生的症状性心房颤动:急性复律与观察等待方法的比较:随机ACWAS试验的原理与设计
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.2016年欧洲心脏病学会(ESC)与欧洲心胸外科学会(EACTS)合作制定的心房颤动管理指南。
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