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微创后路固定联合前路清创融合术治疗胸腰椎化脓性脊柱炎:40例病例系列及文献复习

Minimally invasive posterior fixation and anterior debridement-fusion for thoracolumbar spondylodiscitis: A 40-case series and review of the literature.

作者信息

Farah K, Peyriere H, Graillon T, Prost S, Dufour H, Blondel B, Fuentes S

机构信息

Department of neurosurgery, La Timone university hospital, AP-HM, 13005 Marseille, France; Spine Unit, La Timone university hospital, AP-HM, Marseille, France.

Department of neurosurgery, La Timone university hospital, AP-HM, 13005 Marseille, France; Spine Unit, La Timone university hospital, AP-HM, Marseille, France.

出版信息

Neurochirurgie. 2020 Feb;66(1):24-28. doi: 10.1016/j.neuchi.2019.10.009. Epub 2019 Dec 10.

DOI:10.1016/j.neuchi.2019.10.009
PMID:31836488
Abstract

INTRODUCTION

Pyogenic spondylodiscitis is a rare disease, but incidence is increasing. Reported failure rates following conservative management range from 12% to 18%. The purpose of this study was to determine the safety and efficacy of posterior percutaneous pedicle screw fixation combined with anterior debridement and fusion (ADF) for infective spondylodiscitis in the thoracic and/or lumbar spine.

METHODS

The retrospective study cohort comprised all patients without neurological deficit who underwent minimally invasive posterior and anterior surgery between April 2008 and April 2016 for thoracic and/or lumbar spondylodiscitis.

RESULTS

Forty patients were eligible (16 female: 40%). The lumbar region was affected in 31 cases (77.5%). Source of infection was identified in only 22 cases (55%) and bacteriological identification was obtained in 32 cases (80%). Mean hospital stay was 14.8 days (range, 6-39 days). Complete recovery was achieved in 39 patients (97.5%) at 3 months' follow-up. Mean preoperative local kyphosis angle was 16.1, versus 14 at 1-year (P>0.05). 36 patients (90%) had at least 1 year's follow-up, and fusion was obtained for all these cases.

CONCLUSION

Two-stage minimally invasive surgery is effective and safe for the treatment of single or two-level thoracolumbar spondylodiscitis. It could be an alternative to conventional open surgery or conservative treatment.

摘要

引言

化脓性脊椎间盘炎是一种罕见疾病,但发病率正在上升。据报道,保守治疗后的失败率在12%至18%之间。本研究的目的是确定后路经皮椎弓根螺钉固定联合前路清创融合术(ADF)治疗胸段和/或腰段感染性脊椎间盘炎的安全性和有效性。

方法

回顾性研究队列包括2008年4月至2016年4月间因胸段和/或腰段脊椎间盘炎接受微创前后路手术且无神经功能缺损的所有患者。

结果

40例患者符合条件(16例女性:40%)。31例(77.5%)累及腰椎区域。仅在22例(55%)中确定了感染源,32例(80%)获得了细菌学鉴定。平均住院时间为14.8天(范围6 - 39天)。3个月随访时39例患者(97.5%)完全康复。术前平均局部后凸角为16.1,1年时为14(P>0.05)。36例患者(90%)至少随访1年,所有这些病例均实现融合。

结论

两阶段微创手术治疗单节段或双节段胸腰椎脊椎间盘炎有效且安全。它可以作为传统开放手术或保守治疗的替代方法。

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