儿童脑卒中的机械取栓治疗：三例新病例报告。
Mechanical Thrombectomy in Pediatric Stroke: Report of Three New Cases.
机构信息
Division of Child Neurology, Department of Neurology, Riley Hospital for Children at Indiana University Health and Indiana University School of Medicine, Indianapolis, Indiana.
Division of Child Neurology, Department of Neurology, Riley Hospital for Children at Indiana University Health and Indiana University School of Medicine, Indianapolis, Indiana.
出版信息
J Stroke Cerebrovasc Dis. 2020 Feb;29(2):104551. doi: 10.1016/j.jstrokecerebrovasdis.2019.104551. Epub 2019 Dec 13.
BACKGROUND
Mechanical thrombectomy for treatment of arterial ischemic stroke (AIS) and cerebral venous thrombosis (CVT) is well-studied in adult populations, but not in children.
METHODS
We report 3 new cases of pediatric stroke treated using mechanical thrombectomy. Two cases of AIS and 1 case of CVT were identified from 2018 pediatric stroke clinic records.
RESULTS
Thrombectomy was successful in 1 of the 2 AIS cases and in the CVT case. None of the children were asymptomatic after thrombectomy. One AIS case had good recovery than developed dystonia which responded to treatment; the second AIS case had residual hemiplegia; and the child with CVT had mild school problems.
CONCLUSIONS
Mechanical thrombectomy is being increasingly used for pediatric stroke treatment. This study and recent literature reviews suggest thrombectomy holds promise as a treatment for selected pediatric stroke patients. Questions remain about the safety and efficacy of thrombectomy in children with stroke since large randomized controlled studies are not yet feasible.
背景
机械取栓术治疗动脉缺血性脑卒中（AIS）和脑静脉血栓形成（CVT）在成年人群中已有大量研究，但在儿童中却没有。
方法
我们报告了 3 例使用机械取栓术治疗的儿科脑卒中新病例。2018 年儿科脑卒中门诊记录中发现了 2 例 AIS 和 1 例 CVT。
结果
2 例 AIS 中的 1 例和 CVT 病例的取栓术成功。取栓术后，没有患儿无症状。1 例 AIS 患者恢复良好，但出现了运动障碍，经治疗后得到缓解；另 1 例 AIS 患者仍有偏瘫；CVT 患儿有轻度学习问题。
结论
机械取栓术越来越多地用于儿科脑卒中的治疗。本研究和最近的文献综述表明，取栓术有望成为治疗某些儿科脑卒中患者的一种治疗方法。由于尚未进行大型随机对照研究，因此关于取栓术在儿童脑卒中患者中的安全性和有效性仍存在疑问。
Zotero 插件