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抗磷脂综合征患儿的机械取栓术——病例报告

Mechanical thrombectomy in a pediatric patient with antiphospholipid syndrome-a case report.

作者信息

Kowalczewska Justyna, Stanisławska Katarzyna, Rybacka-Mossakowska Joanna, Juszkat Robert, Michalak Sławomir

机构信息

University Clinical Hospital in Poznan, Poznan University of Medical Sciences, Poznan, Poland.

Department of General and Interventional Radiology, University Clinical Hospital in Poznan, Poznan University of Medical Sciences, Poznan, Poland.

出版信息

Front Med (Lausanne). 2025 Apr 11;12:1530420. doi: 10.3389/fmed.2025.1530420. eCollection 2025.

Abstract

Stroke ranks among the top 10 most common causes of death in children. Recently, there has been a significant increase in the number of strokes in the pediatric population. Mechanical thrombectomy is an uncommon method for treating acute ischemic stroke (AIS) in children. This case report discusses a 13-year-old girl with a history of ischemic stroke for the past 3 months, obesity, hypertension, and antiphospholipid syndrome (APS, treated with rivaroxaban), who suffered another ischemic stroke and underwent mechanical thrombectomy with favorable clinical outcomes. Additionally, the patient was diagnosed with antithrombin III deficiency. It is necessary to identify risk factors for AIS in the pediatric population, such as thrombophilia or autoimmune diseases, such as antiphospholipid syndrome, and to develop guidelines for the use of thrombectomy in children. This method could reduce mortality, improve quality of life, prevent disability, and lower future medical costs.

摘要

中风是儿童十大常见死因之一。近年来,儿科人群中风的数量显著增加。机械取栓术是治疗儿童急性缺血性中风(AIS)的一种不常见方法。本病例报告讨论了一名13岁女孩,她在过去3个月有缺血性中风病史,患有肥胖症、高血压和抗磷脂综合征(APS,使用利伐沙班治疗),该女孩再次发生缺血性中风并接受了机械取栓术,临床结果良好。此外,该患者被诊断为抗凝血酶III缺乏症。有必要确定儿科人群中AIS的危险因素,如易栓症或自身免疫性疾病(如抗磷脂综合征),并制定儿童取栓术的使用指南。这种方法可以降低死亡率、提高生活质量、预防残疾并降低未来的医疗成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/764e/12021898/2762b14dae2f/fmed-12-1530420-g001.jpg

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