[肛管直肠区域恶性黑色素瘤——两例报告]

[Malignant melanoma in the anorectal region--a report of two cases].

作者信息

Kunieda K, Wakahara M, Ando T, Takenouchi N, Chujo T, Azuma S, Saji S, Sakata K, Shimokawa K

机构信息

2nd Dept. of Surgery, Gifu Univ. School of Med.

出版信息

Gan No Rinsho. 1988 Sep;34(11):1613-8.

PMID:3184465

Abstract

Case 1. A 61-year-old male, suffering from an anorectal tumor with anal bleeding, underwent an abdominoperineal rectal amputation with an R3 lymphadenectomy. The tumor was a Stage I (H0, P0, N0, S0) malignant melanoma. Despite DAV (DTIC, ACNU, and VCR) therapy, liver metastasis was detected 1 year later and the patient died 1.5 years after the operation. Case 2. A 80-year-old female, complaining of bloody stool, was diagnosed to have an anorectal malignant melanoma. She was at Stage IV and underwent an abdominoperineal rectal amputation with an R3 lymphadenectomy. The tumor 4.5 X 2.7 X 1.2 cm in size, was diagnosed to be at Stage IV (pm, n2+). She is still alive 4 years later without having received sufficient chemotherapy.

摘要

病例1. 一名61岁男性，患有伴有肛门出血的肛管直肠肿瘤，接受了经腹会阴直肠切除术及R3淋巴结清扫术。肿瘤为I期（H0，P0，N0，S0）恶性黑色素瘤。尽管接受了DAV（达卡巴嗪、阿糖胞苷和长春新碱）治疗，但1年后仍检测到肝转移，患者术后1.5年死亡。病例2. 一名80岁女性，主诉便血，被诊断为肛管直肠恶性黑色素瘤。她处于IV期，接受了经腹会阴直肠切除术及R3淋巴结清扫术。肿瘤大小为4.5×2.7×1.2 cm，被诊断为IV期（pm，n2+）。4年后她仍存活，未接受充分的化疗。