Vettori Erica, Costantinides Fulvia, Nicolin Vanessa, Rizzo Roberto, Perinetti Giuseppe, Maglione Michele, Di Lenarda Roberto
Maxillofacial and Dental Surgical Clinic, Department of Medical, Surgical and Health Sciences, University of Trieste, Piazza dell'Ospitale 1, 34129 Trieste, Italy.
Antibiotics (Basel). 2019 Dec 13;8(4):264. doi: 10.3390/antibiotics8040264.
Complications after tooth extraction may occur because of several factors correlated to the patient's medical history, surgical site or type of intervention. The aim of this retrospective cohort study was to evaluate type and frequency of complications after exodontic surgery, its correlation with antibiotic administration and between patient's related systemic factors. From June 2015 until February 2016 1701 exodontic interventions, for a total of 2322 extracted teeth, were carried out at the Unit of Oral Surgery in Trieste. Descriptive statistic, and backward multiple logistic regressions were performed to identify the variables associated with the presence of post-operative alveolitis or any other post-operative complication. The presence of coagulopathy and smoking habit were related to high risk of post-operative alveolitis (OR = 5.51, = 0.035 and OR = 2.5, = 0.029, respectively). Tooth fracture was found to be correlated with higher probability of post-operative alveolitis ( = 0.001) and concomitant chemotherapy put at a higher risk post-operative complications, including alveolitis (OR = 29.5, = 0.018). According to the present results, antibiotic consumption did not seem to reduce the incidence of post-operative infective complications (alveolitis). A careful analysis of medical history, the adequate surgical technique, and the correct instructions in post-surgical behavior, prevent the insurgence of intra and post-operative complications.
拔牙后的并发症可能由于与患者病史、手术部位或干预类型相关的多种因素而发生。这项回顾性队列研究的目的是评估拔牙手术后并发症的类型和频率、其与抗生素使用以及患者相关全身因素之间的相关性。2015年6月至2016年2月期间,在的里雅斯特口腔外科进行了1701例拔牙手术,共拔除2322颗牙齿。进行了描述性统计和向后多因素逻辑回归分析,以确定与术后干槽症或任何其他术后并发症存在相关的变量。凝血功能障碍和吸烟习惯与术后干槽症的高风险相关(比值比分别为5.51,P = 0.035和2.5,P = 0.029)。发现牙齿折断与术后干槽症的较高概率相关(P = 0.001),同时化疗会增加术后并发症(包括干槽症)的风险(比值比为29.5,P = 0.018)。根据目前的结果,抗生素的使用似乎并未降低术后感染性并发症(干槽症)的发生率。对病史进行仔细分析、采用适当的手术技术以及给予正确的术后行为指导,可预防术中和术后并发症的发生。