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减重手术后吸烟与术后并发症和再入院相关。

Post-Operative Complications and Readmissions Associated with Smoking Following Bariatric Surgery.

机构信息

Surgical Outcomes and Quality Improvement Center (SOQIC), Feinberg School of Medicine, Northwestern University, 633 N St Clair St, 20th Floor, Chicago, IL, 60611, USA.

Department of Surgery, Feinberg School of Medicine, Northwestern University, 633 N St Clair St, 20th Floor, Chicago, IL, 60611, USA.

出版信息

J Gastrointest Surg. 2020 Mar;24(3):525-530. doi: 10.1007/s11605-019-04488-3. Epub 2019 Dec 17.

Abstract

BACKGROUND

The link between smoking and poor postoperative outcomes is well established. Despite this, current smokers are still offered bariatric surgery. We describe the risk of postoperative 30-day complications and readmission following laparoscopic sleeve gastrectomy and laparoscopic Roux-En-Y gastric bypass in smokers.

METHODS

The National Surgical Quality Improvement Program database was queried to identify patients who underwent laparoscopic sleeve gastrectomy and Roux-En-Y gastric bypass from 2012 to 2017. Patient outcomes were compared based on smoking status. Primary outcomes included 30-day readmission and death or serious morbidity. Secondary outcomes included wound and respiratory complications. Multivariable logistic regression was used to determine the association between smoking status and measured outcomes.

RESULTS

Of the 133,417 patients who underwent bariatric surgery, 12,424 (9.3%) were smokers. Smokers more frequently experienced readmission (4.9% v 4.1%, p < 0.001), death or serious morbidity (3.8% v 3.4%, p = 0.019), wound complications (2% v 1.4%, p < 0.001), and respiratory complications (0.8% v 0.5%, p < 0.001). The likelihood of death or serious morbidity (OR 1.13, 95% CI 1.01-1.26), readmission (OR 1.21, 95% CI 1.10-1.33), wound (OR 1.44, 95% CI 1.24-1.68), and respiratory complications (OR 1.69, 95% CI 1.34-2.14) were greater in smokers. The adjusted ORs remained significant on subgroup analysis of laparoscopic sleeve gastrectomy and Roux-En-Y gastric bypass patients, with the exception of death or serious morbidity in laparoscopic Roux-En-Y gastric bypass (OR 1.04, 95% CI 0.89-1.24).

CONCLUSIONS

Smokers undergoing bariatric surgery experience significantly worse 30-day outcomes when compared with non-smokers. There should be a continued emphasis on perioperative smoking cessation for patients being evaluated for bariatric surgery.

摘要

背景

吸烟与术后不良结局之间存在关联,这一点已经得到了充分证实。尽管如此,目前仍有吸烟者接受减重手术。我们描述了吸烟者接受腹腔镜袖状胃切除术和腹腔镜 Roux-en-Y 胃旁路术后 30 天内并发症和再入院的风险。

方法

从 2012 年至 2017 年,国家外科质量改进计划数据库中检索接受腹腔镜袖状胃切除术和 Roux-en-Y 胃旁路术的患者。根据吸烟状况比较患者的术后结局。主要结局包括 30 天再入院和死亡或严重发病率。次要结局包括伤口和呼吸系统并发症。多变量逻辑回归用于确定吸烟状况与测量结局之间的关联。

结果

在接受减重手术的 133417 名患者中,有 12424 名(9.3%)是吸烟者。吸烟者再入院的比例更高(4.9%比 4.1%,p<0.001),死亡或严重发病率(3.8%比 3.4%,p=0.019),伤口并发症(2%比 1.4%,p<0.001)和呼吸系统并发症(0.8%比 0.5%,p<0.001)。吸烟者死亡或严重发病率(OR 1.13,95%CI 1.01-1.26)、再入院(OR 1.21,95%CI 1.10-1.33)、伤口(OR 1.44,95%CI 1.24-1.68)和呼吸系统并发症(OR 1.69,95%CI 1.34-2.14)的可能性更大。在腹腔镜袖状胃切除术和 Roux-en-Y 胃旁路术患者的亚组分析中,调整后的 OR 仍然具有统计学意义,除了腹腔镜 Roux-en-Y 胃旁路术的死亡或严重发病率(OR 1.04,95%CI 0.89-1.24)外。

结论

与非吸烟者相比,接受减重手术的吸烟者 30 天结局明显更差。对于接受减重手术评估的患者,应继续强调围手术期戒烟。

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