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减肥手术后两到四年的自我报告胃肠道症状。一项比较Roux-en-Y胃旁路术和腹腔镜袖状胃切除术的横断面研究。

Self-Reported Gastrointestinal Symptoms Two To Four Years After Bariatric Surgery. A Cross-Sectional Study Comparing Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy.

作者信息

Thorsen Brit, Gjeilo Kari Hanne, Sandvik Jorunn, Follestad Turid, Græslie Hallvard, Nymo Siren

机构信息

Nord-Trøndelag Hospital Trust, Clinic of Surgery, Namsos Hospital, Namsos, Norway.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.

出版信息

Obes Surg. 2021 Oct;31(10):4338-4346. doi: 10.1007/s11695-021-05605-5. Epub 2021 Aug 10.

Abstract

BACKGROUND

Roux-en-Y gastric bypass (RYGBP) and laparoscopic sleeve gastrectomy (LSG) are efficient methods for weight loss (WL) and WL maintenance in severe obesity. However, the knowledge of gastrointestinal (GI) symptoms after surgery is limited. This study aimed to compare the severity of GI symptoms, pain, and self-rated health 2 to 4 years after RYGBP and LSG surgery.

METHODS

In this cross-sectional study, RYGBP and LSG patients answered a questionnaire including the Gastrointestinal Symptom Rating Scale (GSRS), questions from the Brief Pain Inventory (BPI), and self-rated health (SRH).

RESULTS

A total of 172/303 (57%) responded, RYGBP (n=73) and LSG (n=99). The mean age was 45.3 (SD 11.1) years (74% females). There was no evidence of a difference in total GSRS scores between the surgical methods (p=0.638). There were higher scores of reflux symptoms in LSG vs. RYGBP (both median 1, 75-percentile 2.5 vs. 1.0, p <0.001) and higher consumption of acid-reducing medication after LSG (32% vs. 12%, p <0.001). Pain scores were low in both groups; however, average abdominal pain was higher for RYGBP, median 2 (IQR 0-4) vs. median 1 (IQR 0-3) for LSG (p = 0.025). There was no significant difference in SRH.

CONCLUSIONS

Patients undergoing RYGBP and LSG surgery reported similar total GSRS scores and low pain scores 2 to 4 years after surgery. However, reflux symptoms and use of acid-reducing medication occurred more frequently after LSG surgery, while abdominal pain was more frequent in RYGBP surgery. These findings are important for surgical decision-making and follow-up.

摘要

背景

Roux-en-Y胃旁路术(RYGBP)和腹腔镜袖状胃切除术(LSG)是重度肥胖患者减重及维持体重的有效方法。然而,关于术后胃肠道(GI)症状的了解有限。本研究旨在比较RYGBP和LSG手术后2至4年胃肠道症状、疼痛及自我健康评分的严重程度。

方法

在这项横断面研究中,RYGBP和LSG患者回答了一份问卷,包括胃肠道症状评定量表(GSRS)、简明疼痛问卷(BPI)中的问题以及自我健康评分(SRH)。

结果

共有172/303(57%)的患者做出回应,其中RYGBP组73例,LSG组99例。平均年龄为45.3(标准差11.1)岁(74%为女性)。没有证据表明两种手术方法的GSRS总分存在差异(p = 0.638)。与RYGBP相比,LSG的反流症状评分更高(中位数均为1,第75百分位数分别为2.5和1.0,p < 0.001),且LSG术后使用抑酸药物的比例更高(32%对12%,p < 0.001)。两组的疼痛评分均较低;然而,RYGBP的平均腹痛更高,中位数为2(四分位间距0 - 4),而LSG为中位数1(四分位间距0 - 3)(p = 0.025)。自我健康评分无显著差异。

结论

接受RYGBP和LSG手术的患者在术后2至4年报告的GSRS总分相似且疼痛评分较低。然而,LSG术后反流症状和使用抑酸药物更为频繁,而RYGBP手术中腹痛更为常见。这些发现对手术决策和随访具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/920e/8458174/99fbe001f501/11695_2021_5605_Fig1_HTML.jpg

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