Vojvodic Aleksandra, Tirant Michael, Nardo Veronica di, Lotti Torello, Wollina Uwe
Department of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia.
Department of Dermatology, University of Rome "G. Marconi", Rome, Italy.
Open Access Maced J Med Sci. 2019 Sep 10;7(18):2969-2975. doi: 10.3889/oamjms.2019.680. eCollection 2019 Sep 30.
The concept of immunocompromised districts of skin has been developed by Ruocco and helps to explain certain aspects of the macromorphology of skin diseases. This concept unites the isomorphic response of Koebner and the isotopic response of Wolf.
We present different cutaneous conditions which can lead to immunocompromised districts of skin such as scars, radiodermatitis, lymphedema, disturbed innervation or mechanical friction etc. Typical and rarer skin disorders associated with them are discussed and illustrated by their observations.
At this moment, we wish to inform dermatologists and non-dermatologists about Ruocco's concept and its implications.
皮肤免疫功能低下区域的概念由鲁科提出,有助于解释皮肤病大体形态学的某些方面。这一概念将科布纳的同形反应和沃尔夫的同位素反应统一起来。
我们展示了不同的皮肤状况,这些状况可导致皮肤免疫功能低下区域,如瘢痕、放射性皮炎、淋巴水肿、神经支配紊乱或机械摩擦等。文中讨论了与之相关的典型和罕见皮肤病,并通过观察结果进行了说明。
目前,我们希望向皮肤科医生和非皮肤科医生介绍鲁科的概念及其影响。