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有限区域减压、椎间融合及椎弓根螺钉内固定治疗退变性腰椎管狭窄症伴腰椎不稳:至少12个月随访的观察性研究

The limited area decompression, intervertebral fusion, and pedicle screw fixation for treating degenerative lumbar spinal stenosis with instability: Follow-up at least 12 months an observational study.

作者信息

Yang Fengguang, Ren Enhui, Yang Liang, Wang Yonggang, Hu Xuchang, Yang Yong, Kang Xuewen

机构信息

Lanzhou University Second Hospital.

Orthopedics Key laboratory of Gansu Province, Lanzhou.

出版信息

Medicine (Baltimore). 2019 Dec;98(50):e18277. doi: 10.1097/MD.0000000000018277.

Abstract

The aim of the study was to evaluate the clinical effect of the limited area decompression, intervertebral fusion, and pedicle screw fixation for treating degenerative lumbar spinal stenosis (DLSS) with instability. Hemilaminectomy decompression, intervertebral fusion, and pedicle screw fixation for treating DLSS with instability as the control group.Follow-up of 54 patients (26 males and 28 females; average age, 59.74 ± 10.38 years) with DLSS with instability treated by limited area decompression, intervertebral fusion, and pedicle screw fixation (LIFP group), and 52 patients as control group with hemilaminectomy decompression, intervertebral fusion, and pedicle screw fixation (HIFP group). We assessed clinical effect according to the patients' functional outcome grading (good to excellent, fair, or poor), Oswestry Disability Index (ODI) and visual analogue scale (VAS) for low back pain and lower limb pain, which was administered preoperatively and at 3, 6, and 12 months postoperatively. Fusion status was assessed by radiologists at the last follow-up. Treatment satisfaction was assessed according to the subjective evaluations of the patients.At the 12-month follow-up, 96.2% (52/54) and 90.3% (47/52) of group LIFP and HIFP belonged to good to excellent outcome categories, respectively, while 3.7% (2/54) and 9.6% (5/52) of group LIFP and HIFP belonged to fair respectively, neither group belonged to poor. Satisfaction rates of patients in group LIFP and group HIFP were 98.1% (53/54) and 92.3% (48/52), respectively. The patients' functional outcome grading and satisfaction rate in group LIFP were better than that in group HIFP. The VAS for low back and lower limb pain and the ODI improved significantly during the 12 months after surgery (all P < .001) in 2 groups. The VAS for low back and lower limb pain were no difference between two groups, however, the ODI of group LIFP was lower than that of group HIFP (P < .001). All patients achieved radiological fusion.The limited area decompression, intervertebral fusion, and pedicle screw fixation had a satisfactory effect on patients with DLSS with instability.

摘要

本研究的目的是评估有限区域减压、椎间融合和椎弓根螺钉固定治疗伴有不稳的退变性腰椎管狭窄症(DLSS)的临床效果。以半椎板切除术减压、椎间融合和椎弓根螺钉固定治疗伴有不稳的DLSS作为对照组。对54例(男26例,女28例;平均年龄59.74±10.38岁)采用有限区域减压、椎间融合和椎弓根螺钉固定治疗的伴有不稳的DLSS患者(LIFP组)以及52例采用半椎板切除术减压、椎间融合和椎弓根螺钉固定的对照组患者(HIFP组)进行随访。我们根据患者的功能结果分级(优至良、尚可或差)、Oswestry功能障碍指数(ODI)以及用于评估腰背痛和下肢痛的视觉模拟评分(VAS)对临床效果进行评估,这些评估在术前以及术后3、6和12个月进行。在末次随访时由放射科医生评估融合状态。根据患者的主观评价评估治疗满意度。在12个月随访时,LIFP组和HIFP组分别有96.2%(52/54)和90.3%(47/52)属于优至良的结果类别,而LIFP组和HIFP组分别有3.7%(2/54)和9.6%(5/52)属于尚可,两组均无差的情况。LIFP组和HIFP组患者的满意度分别为98.1%(53/54)和92.3%(48/52)。LIFP组患者的功能结果分级和满意度高于HIFP组。两组患者术后12个月期间腰背痛和下肢痛的VAS以及ODI均显著改善(均P<0.0

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9a1/6922491/83789b1be3c2/medi-98-e18277-g002.jpg

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