Department of Spine Surgery, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China.
Department of Orthopedics, Shanghai General Hospital of Nanjing Medical University, Songjiang 201600, Shanghai, China.
Int J Surg. 2018 Feb;50:72-78. doi: 10.1016/j.ijsu.2017.12.031. Epub 2018 Jan 9.
The aim of this study was to evaluate the clinical and radiologic results of multisegmental transforaminal enlarged decompression (TED) plus posterior pedicle screw fixation in the treatment of multilevel lumbar spinal canal stenosis (LSCS) with lumbar instability (MLSCSI).
113 patients with MLSCSI underwent surgery were recruited in this study. All patients were suffering from symptoms typical of degenerative LSCS and treated with either TED plus fusion (TEDF group) or conventional laminectomy plus fusion (CLF group). Clinical and radiologic parameters were evaluated. The clinical data, including Visual Analog Scale (VAS) for back and leg pain, Oswestry Disability Index (ODI), operative time, intraoperative blood loss, postoperative drainage, hospital stay, and the rate of postoperative complications, were assessed. With respect to radiologic parameters, mean disc height (MDH) and lumbar lordotic angle (LLA) were measured using plain radiographs. Patient satisfaction was evaluated according to the North American Spine Society (NASS) Outcome Questionnaire.
No serious complications occurred during the follow-up. The operative time was significantly shorter for TEDF group than for CLF group, and similar results were found with regard to the blood loss and postoperative drainage (p < .05). The improvements in ODI, leg and back VAS scores were observed in both groups after surgery and follow-up (P < .05). In the last follow-up, ODI and back VAS scores in TEDF group were significantly higher than those in CLF group (P < .05). Regarding radiologic variants, MDH and LLA were improved after operation for 3 months (P > .05) and were all well maintained in the final follow-up in both groups. Patients in TEDF group were more satisfied than patients in the CLF group (85.2% vs 76.9%, p = .092).
Satisfactory clinical and radiological outcomes can be achieved with the use of multisegmental TED plus lumbar fusion for the treatment of MLSCSI. This technique can reduce surgically induced instability and obviously improve the symptoms and signs of the patients, suggesting a safe and effective therapeutic procedure for MLSCSI.
本研究旨在评估多节段经椎间孔扩大减压(TED)联合后路椎弓根螺钉固定治疗合并腰椎不稳的多节段腰椎管狭窄症(MLSCSI)的临床和影像学结果。
本研究共纳入 113 例合并腰椎不稳的多节段腰椎管狭窄症(MLSCSI)患者,所有患者均有退变性腰椎管狭窄症的典型症状,并分别采用经椎间孔扩大减压融合术(TEDF 组)或传统椎板切除术融合术(CLF 组)治疗。评估临床和影像学参数。评估临床资料,包括腰背疼痛视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)、手术时间、术中出血量、术后引流量、住院时间和术后并发症发生率。影像学参数方面,采用 X 线片测量平均椎间盘高度(MDH)和腰椎前凸角(LLA)。根据北美脊柱协会(NASS)结果问卷评估患者满意度。
所有患者随访期间均未发生严重并发症。TEDF 组手术时间明显短于 CLF 组,术中出血量和术后引流量也明显少于 CLF 组(p < .05)。两组术后及随访时 ODI、腿痛和腰痛 VAS 评分均有改善(P < .05)。末次随访时,TEDF 组 ODI 和腰痛 VAS 评分明显高于 CLF 组(P < .05)。影像学方面,术后 3 个月 MDH 和 LLA 均有改善(P > .05),两组末次随访时均得到良好维持。TEDF 组患者满意度高于 CLF 组(85.2% vs 76.9%,p = .092)。
多节段经椎间孔扩大减压联合腰椎融合术治疗合并腰椎不稳的多节段腰椎管狭窄症可获得满意的临床和影像学结果。该技术可减少手术引起的不稳定,明显改善患者的症状和体征,为合并腰椎不稳的多节段腰椎管狭窄症提供了一种安全有效的治疗方法。