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寰枢脊髓角作为 A 型颅底凹陷症术后神经功能结局的独立影像学预测指标。

Cervicomedullary angle as an independent radiological predictor of postoperative neurological outcome in type A basilar invagination.

机构信息

Department of Orthopedics, Changzheng Hospital, The Second Military Medical University, Shanghai, People's Republic of China.

Department of General medicine, The Second affiliated hospital of Xi'an Jiaotong University, Shannxi, People's Republic of China.

出版信息

Sci Rep. 2019 Dec 18;9(1):19364. doi: 10.1038/s41598-019-55780-w.

Abstract

To propose an independent radiological index to evaluate surgical outcomes of A type basilar invagination, a retrospective study was conducted to compare the clinical outcome between procedures 1 and 2 by applying intraoperative consistent traction and manual reduction. Moreover, the atlantodental interval (ADI), cervicomedullary angle (CMA), bilateral sagittal inclination of atlantoaxial joint (SIAA) were measured and compared to pre-operation. Postoperatively, only these patients undergoing procedure 2 achieved significant neurological improvement. The ADIs and the SIAAs decreased in both groups, these differences are statistically significant between pre- and post- operation. For postoperative CMAs, only these patients undergoing modified surgery gained significant improvement of angle with mean 141°. We concluded that the CMA or SIAA could be a radiological predictor to evaluate surgical outcome in BI, among which the CMA is a more independent and easily measurable predictor that is closely correlated with satisfactory neurological improvements. Moreover, procedure 2 with intraoperative resistant cranial traction and manual reduction can help us achieve a good CMA.

摘要

为了提出一个独立的影像学指标来评估 A 型颅底凹陷症的手术效果,本研究回顾性比较了术中持续牵引和手动复位两种方法的临床效果。同时,测量并比较了寰齿间距(ADI)、寰枢角(CMA)、寰枢侧块双侧矢状倾斜角(SIAA)等影像学指标与术前的差异。术后,仅接受改良手术的患者的神经功能显著改善。两组患者的 ADI 和 SIAA 均减小,术后与术前比较差异有统计学意义。对于术后 CMA,仅接受改良手术的患者的角度有显著改善,平均为 141°。我们的结论是,CMA 或 SIAA 可以作为评估 BI 手术效果的影像学指标,其中 CMA 是一个更独立和易于测量的预测指标,与满意的神经功能改善密切相关。此外,术中抵抗性颅牵引和手动复位的改良手术方法可以帮助我们获得良好的 CMA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b760/6920483/c9e2184aab27/41598_2019_55780_Fig1_HTML.jpg

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