利用快速 HIV 自检筛查潜在性伴侣：ISUM 研究结果。
Use of Rapid HIV Self-Test to Screen Potential Sexual Partners: Results of the ISUM Study.
机构信息
Division of Gender, Sexuality and Health, HIV Center for Clinical and Behavioral Studies, NY State Psychiatric Institute and Columbia University, 1051 Riverside Drive, Unit 15, New York, NY, 10032, USA.
Department of Medicine, Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, CA, USA.
出版信息
AIDS Behav. 2020 Jun;24(6):1929-1941. doi: 10.1007/s10461-019-02763-7.
ISUM ("I'll show you mine") was a randomized controlled trial in which 272 transgender women and men who have sex with men in New York, NY (NYC) and San Juan, Puerto Rico (SJU) were assigned to an intervention group (n = 136), in which they had access to free HIV self-testing (ST) kits, or to a control group (n = 136). The trial aimed to determine whether the intervention group would use ST to screen sexual partners and have fewer condomless anal intercourse (CAI) occasions with serodiscordant or unknown status partners than the control group. The intervention group had on average 10 (32%) fewer CAI occasions; though clinically relevant, this difference fell short of statistical significance (p = .08). In NYC (n = 166) intervention participants had significantly fewer CAI occasions, whereas in SJU (n = 106) they reported non-significantly more CAI occasions. Two devastating hurricanes hit SJU during the study and may have impacted results in unmeasured ways.
ISUM（“我会向你展示我的”）是一项随机对照试验，共有 272 名纽约市（NYC）和波多黎各圣胡安（SJU）的跨性别女性和男男性行为者参与，他们被随机分配到干预组（n=136）或对照组（n=136）。干预组可以免费获得 HIV 自我检测（ST）试剂盒，而对照组则不能。该试验旨在确定干预组是否会使用 ST 来筛查性伴侣，与血清不一致或未知状态的伴侣发生无保护肛交（CAI）的次数是否少于对照组。干预组的 CAI 次数平均减少了 10 次（32%）；尽管这在临床上有意义，但差异没有达到统计学显著性（p=0.08）。在纽约市（n=166），干预组参与者的 CAI 次数明显减少，而在圣胡安（n=106），他们报告的 CAI 次数则没有明显增加。在研究期间，两场毁灭性的飓风袭击了圣胡安，可能以未测量的方式影响了结果。
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