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后连续曲线撕囊联合前段玻璃体切除术与无前段玻璃体切除术的小儿白内障手术中的光学襻扣固定术。

Posterior continuous curvilinear capsulorhexis with anterior vitrectomy vs optic capture buttonholing without anterior vitrectomy in pediatric cataract surgery.

机构信息

From the Department of Ophthalmology, Goethe University, Frankfurt, Germany.

出版信息

J Cataract Refract Surg. 2022 Jul 1;48(7):831-837. doi: 10.1097/j.jcrs.0000000000000846.

Abstract

PURPOSE

To investigate long-term complications after pediatric cataract surgery with implantation of a heparin-coated polymethyl methacrylate intraocular lens (PMMA IOL) and posterior continuous curvilinear capsulorhexis (PCCC) with anterior vitrectomy vs PCCC without anterior vitrectomy with optic capture buttonholing.

SETTING

Department of Ophthalmology, Goethe University, Frankfurt, Germany.

DESIGN

Prospective randomized clinical trial.

METHODS

Eyes with unilateral or bilateral congenital cataract without further pathologies or former surgeries were randomly assigned in 2 groups: cataract removal, IOL implantation, and PCCC with anterior vitrectomy (group A) or posterior optic buttonholing without anterior vitrectomy (group B). The main outcome measures were posterior capsule opacification (PCO), complication rates, and refractive development.

RESULTS

58 eyes of 41 pediatric cataract surgery patients were included. The mean age at the time of operation was 66.05 months (±29.39). In group A (n = 26), 2 eyes required treatment for PCO, whereas the optic axis remained clear in all eyes in group B (n = 30), which was statistically insignificant. In addition, group B had a slightly lower rate of complications. The mean spherical equivalent after a mean postoperative follow-up of 6.5 years was -0.11 ± 2.51 diopters (D) (-5.0 to +4.0 D) in group A and -0.08 ± 2.14 D (-5.0 to +4.0 D) in group B, which was also statistically insignificant.

CONCLUSIONS

Optic capture with a heparin-coated PMMA IOL proved to be a safe technique in the prevention of secondary cataract formation without a higher rate of complications and the necessity of vitrectomy.

摘要

目的

研究肝素涂层聚甲基丙烯酸甲酯(PMMA)人工晶状体(IOL)植入联合后囊连续环形撕囊(PCCC)与前玻璃体切割术治疗与单纯后囊连续环形撕囊联合前玻璃体切割的肝素涂层 PMMA IOL 眼内固定术治疗小儿白内障术后长期并发症的效果。

设置

德国法兰克福歌德大学眼科。

设计

前瞻性随机临床试验。

方法

对无其他病变或既往手术史的单侧或双侧先天性白内障患儿的双眼随机分为两组:白内障切除、IOL 植入及 PCCC 联合前玻璃体切割术(A 组)或单纯后囊连续环形撕囊联合前玻璃体切割的肝素涂层 PMMA IOL 眼内固定术(B 组)。主要观察指标为后发性白内障(PCO)、并发症发生率和屈光发育。

结果

41 例小儿白内障手术患者 58 只眼纳入研究。手术时平均年龄为 66.05 个月(±29.39)。A 组(n=26)中有 2 只眼因 PCO 需治疗,而 B 组(n=30)所有眼的视轴均保持透明,差异无统计学意义。此外,B 组并发症发生率略低。术后平均随访 6.5 年,A 组平均等效球镜为-0.11±2.51 屈光度(D)(-5.0 至+4.0 D),B 组为-0.08±2.14 D(-5.0 至+4.0 D),差异均无统计学意义。

结论

肝素涂层 PMMA IOL 眼内固定术在预防继发性白内障形成方面是安全的,其并发症发生率和玻璃体切割术的必要性并未增加。

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