中心性浆液性脉络膜视网膜病变的视网膜下高反射物质。
Subretinal hyperreflective material in central serous chorioretinopathy.
机构信息
Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases , L V Prasad Eye Institute, Hyderabad, India.
Department of Ophthalmology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
出版信息
Indian J Ophthalmol. 2020 Jan;68(1):126-129. doi: 10.4103/ijo.IJO_265_19.
PURPOSE
To describe the the appearance and behavior of subretinal hyperreflective material (SHRM) in eyes with central serous chorioretinopathy (CSCR).
METHODS
This retrospective study included 20 eyes of 20 patients with CSCR presenting with SHRM, defined as sub-retinal deposits that appear hyper-reflective on OCT The eyes underwent either laser (15 eyes) or observation (5 eyes). Optical coherence tomography and fundus fluorescein angiography (FFA) characteristics were analyzed at baseline and resolution of neurosensory detachment, which were then co-related with the visual acuity at resolution.
RESULTS
Improvement in vision was seen in 16 eyes. Ellipsoid zone damage (P = 0.03) and external limiting membrane (ELM) damage (P = 0.000) at resolution; diffuse retinal pigment epithelium (RPE) abnormalities on FFA (P = 0.04), and the presence of scar (P = 0.000), were associated with poor visual outcome in univariate analysis. ELM damage at resolution was statistically significant (P = 0.001) in multivariate analysis.
CONCLUSION
CSCR with SHRM have a good visual prognosis. ELM damage at resolution corelates with a poor visual acuity at resolution.
目的
描述中心性浆液性脉络膜视网膜病变（CSCR）患者中视网膜下高反射物质（SHRM）的外观和行为。
方法
本回顾性研究纳入了 20 例伴有 SHRM 的 CSCR 患者的 20 只眼，定义为 OCT 上呈现视网膜下沉积物的高反射物质。这些眼睛接受了激光（15 只眼）或观察（5 只眼）治疗。在神经感觉脱离的缓解时，对光学相干断层扫描（OCT）和眼底荧光血管造影（FFA）特征进行分析，并将其与缓解时的视力相关联。
结果
16 只眼的视力得到改善。缓解时的椭圆体带损伤（P = 0.03）和外界膜（ELM）损伤（P = 0.000）；FFA 上弥漫性视网膜色素上皮（RPE）异常（P = 0.04），以及存在瘢痕（P = 0.000），在单变量分析中与视力不良结果相关。多变量分析显示，缓解时的 ELM 损伤具有统计学意义（P = 0.001）。
结论
伴有 SHRM 的 CSCR 具有良好的视力预后。缓解时的 ELM 损伤与缓解时的低视力相关。
Zotero 插件