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超声乳化白内障吸除术联合黏弹剂分离小梁切除术与白内障青光眼联合手术治疗原发性闭角型青光眼合并白内障的疗效比较。

Combined phacoemulsification-viscosynechialysis-trabeculotomy vs phacotrabeculectomy in uncontrolled primary angle-closure glaucoma with cataract.

机构信息

Faculty of Medicine, Mansoura University, Egypt.

Faculty of Medicine, Alexandria University, Egypt.

出版信息

J Cataract Refract Surg. 2019 Dec;45(12):1738-1745. doi: 10.1016/j.jcrs.2019.07.031.

DOI:10.1016/j.jcrs.2019.07.031
PMID:31856984
Abstract

PURPOSE

To compare the effect on intraocular pressure (IOP) of phacoemulsification combined with viscosynechialysis and trabeculotomy with that of phacoemulsification combined with trabeculectomy in eyes with primary angle-closure glaucoma (PACG) and visually significant cataract.

SETTING

Mansoura Ophthalmic Center, Mansoura University, Egypt.

DESIGN

Prospective case series.

METHODS

This prospective randomized study included patients with uncontrolled PACG and visually significant cataract presenting between 2012 and 2017. The eyes were randomized to phacoemulsification combined with viscosynechialysis and trabeculotomy (phaco-viscosynechialysis group) or phacoemulsification combined with trabeculectomy (phacotrabeculectomy group). Success (true and qualified) (IOP <18 mm Hg without sight-threatening complications) was studied 24 months postoperatively. Intraoperative complications were noted. The primary outcome measure was the IOP before and after surgery.

RESULTS

The study comprised 59 eyes of 59 patients with a mean age of 59.8 years ± 6.8 (SD) in the phaco-viscosynechialysis group (30 eyes) and 60.3 ± 6.3 years in the phacotrabeculectomy group (29 eyes) (P = .704). The mean preoperative IOP was 28.7 ± 2.14 mm Hg in the phaco-viscosynechialysis group and 28.5 ± 2.11 mm Hg in the phacotrabeculectomy group; the mean at 24 months was 14.5 ± 2.8 mm Hg and 17.3 ± 2.2 mm Hg, respectively (P < .001). The total success rate at 24 months was 90% and 83%, respectively.

CONCLUSION

Although both techniques were relatively safe and effective in reducing IOP for at least 2 years in eyes with PACG, combined phacoemulsification-viscosynechialysis-trabeculotomy gave better outcomes.

摘要

目的

比较超声乳化白内障吸除联合黏弹剂分离和小梁切开术与超声乳化白内障吸除联合小梁切除术治疗原发性闭角型青光眼(PACG)合并有临床意义白内障眼的眼压(IOP)影响。

设置

埃及曼苏拉大学曼苏拉眼科中心。

设计

前瞻性病例系列。

方法

本前瞻性随机研究纳入了 2012 年至 2017 年间患有未控制的 PACG 且伴有临床显著白内障的患者。这些眼随机分为超声乳化白内障吸除联合黏弹剂分离和小梁切开术(超声乳化黏弹剂分离小梁切开术组)或超声乳化白内障吸除联合小梁切除术(超声乳化小梁切除术组)。术后 24 个月评估手术成功(真性和合格性)(IOP<18mmHg 且无威胁视力的并发症)。术中并发症也被记录。主要观察指标是手术前后的 IOP。

结果

该研究共纳入 59 只眼 59 例患者,其中超声乳化黏弹剂分离小梁切开术组 30 只眼,平均年龄为 59.8±6.8(标准差)岁;超声乳化小梁切除术组 29 只眼,平均年龄为 60.3±6.3 岁(P=0.704)。超声乳化黏弹剂分离小梁切开术组术前平均 IOP 为 28.7±2.14mmHg,术后 24 个月为 14.5±2.8mmHg;超声乳化小梁切除术组术前平均 IOP 为 28.5±2.11mmHg,术后 24 个月为 17.3±2.2mmHg(P<0.001)。术后 24 个月总成功率分别为 90%和 83%。

结论

尽管两种技术在至少 2 年内降低 PACG 眼的 IOP 都相对安全且有效,但联合超声乳化白内障吸除-黏弹剂分离-小梁切开术的效果更好。

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