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本文引用的文献

1
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.2015年美国甲状腺协会成人甲状腺结节和分化型甲状腺癌管理指南：美国甲状腺协会甲状腺结节和分化型甲状腺癌指南工作组
Thyroid. 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020.
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Primary squamous cell carcinoma of thyroid: a case report and review of literature.甲状腺原发性鳞状细胞癌：一例病例报告及文献复习
Head Neck Oncol. 2012 Mar 27;4:8. doi: 10.1186/1758-3284-4-8.
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Papillary thyroid carcinoma: differential diagnosis and prognostic values of its different variants: review of the literature.甲状腺乳头状癌：不同变异型的鉴别诊断及预后价值：文献综述
ISRN Oncol. 2011;2011:915925. doi: 10.5402/2011/915925. Epub 2011 Dec 6.
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Papillary thyroid carcinoma: an update.甲状腺乳头状癌：更新。
Mod Pathol. 2011 Apr;24 Suppl 2:S1-9. doi: 10.1038/modpathol.2010.129.
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The role of thyrotropin suppression in patients with differentiated thyroid carcinoma.促甲状腺激素抑制在分化型甲状腺癌患者中的作用。
Ir Med J. 2010 Jul-Aug;103(7):202-5.
6
Coexistence of primary squamous cell carcinoma of thyroid with classic papillary thyroid carcinoma.甲状腺原发性鳞状细胞癌与经典型甲状腺乳头状癌共存。
Pathol Int. 2008 Dec;58(12):797-800. doi: 10.1111/j.1440-1827.2008.02314.x.
7
Revision thyroid surgery - technical considerations.
Otolaryngol Clin North Am. 2008 Dec;41(6):1169-83, x. doi: 10.1016/j.otc.2008.05.002.
8
Thyroid carcinoma with discharging sinus -- a rarity: a case report.伴有窦道形成的甲状腺癌——罕见病例：一例报告
J Med Case Rep. 2008 Feb 27;2:64. doi: 10.1186/1752-1947-2-64.
9
Respiratory distress caused by radioiodine therapy in patients with differentiated thyroid cancer.
Ann Nucl Med. 2006 Aug;20(7):499-502. doi: 10.1007/BF02987260.
10
Thyroid papillary carcinoma recurring as squamous cell carcinoma: report of a case.甲状腺乳头状癌复发为鳞状细胞癌：1例报告
Surg Today. 2006;36(2):171-4. doi: 10.1007/s00595-005-3107-3.

病例罕见：伴鳞状化生的乳头状甲状腺癌合并慢性渗出性溃疡

A Case Rarity: Papillary Thyroid Carcinoma with Squamous Metaplasia Complicated with Chronic Discharging Ulcers.

作者信息

Wan Sohaimi Wan Fatihah, Lee Y F, Mat Nawi Norazlina, Mohd Rohani Mohd Fazrin, Sapiai Nur Asma

机构信息

1Department of Nuclear Medicine, Radiotherapy and Oncology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan Malaysia.

2Hospital Universiti Sains Malaysia (Hosp USM), 16150 Kubang Kerian, Kelantan Malaysia.

出版信息

Indian J Surg Oncol. 2019 Dec;10(4):676-678. doi: 10.1007/s13193-019-00977-8. Epub 2019 Sep 2.

DOI:10.1007/s13193-019-00977-8
PMID:31857764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6895325/
Abstract

We report a unique case of differentiated thyroid carcinoma (DTC) with squamous metaplasia complicated with chronic discharging ulcer. A 76-year-old gentleman was referred to us after defaulted treatment 1 year post-total thyroidectomy. He presented to us with long-standing chronic, non-healing, ulcerative and discharging wound at the anterior neck at previous total thyroidectomy scar. The primary tumour was histologically diagnosed as papillary malignant cells with extensive squamous metaplasia. Squamous metaplasia is a rare finding in thyroid carcinoma that carried a poorer prognostic factor.

摘要

我们报告了一例独特的分化型甲状腺癌（DTC），伴有鳞状化生并合并慢性流脓性溃疡。一名76岁男性在全甲状腺切除术后1年未接受治疗后转诊至我院。他因先前全甲状腺切除术后颈部前方长期存在慢性、不愈合、溃疡性且流脓的伤口前来就诊。原发性肿瘤经组织学诊断为具有广泛鳞状化生的乳头状恶性细胞。鳞状化生在甲状腺癌中是一种罕见的表现，提示预后较差。