Ruiz-Mar Gabriela, Ruelas-Ayala Alondra, Ornelas-Oñate Luis Alfredo, Ramirez-Velasquez Jorge Enrique
Department of Bariatric Surgery, Hospital General de Mexico, Ciudad de México, CDMX, Mexico.
Arq Bras Cir Dig. 2019 Dec 20;32(4):e1476. doi: 10.1590/0102-672020190001e1476. eCollection 2019.
Obesity is a major health problem. One anastomosis-gastric bypass (OAGB) is a restrictive and malabsorptive weight loss surgery that carries the same characteristics of Roux-en-Y gastric bypass in its status as a weight loss mechanism; but, its results remain controversial.
To describe the technique and outcomes of OAGB and its effects on weight loss and remission of comorbidities.
Retrospective review of all patients who underwent OAGB procedure from January 2017 to January 2018. Patients' baseline characteristics were recorded. The routine in follow-up were at 1, 3, 6 and 12 months.
A total of 51 patients underwent OAGB. The mean age was 43.8±9.3 years, mean weight was 125±31 and mean BMI was 55.8±12 kg/m2. With regard to comorbidities, 64.7% had type 2 diabetes mellitus (T2DM), 43.1% systemic arterial hypertension (SAH) and 51% dyslipidemia. The BMI decreased for 48.4±1.3 to 31±4.4 at 12 months (p=0.0001) and we obtained an average decreased of 65% excess weight loss (EWL) at 12 months of follow-up. There was improvement in the values of total cholesterol (CT) (p=0.348); triglycerides (TGC) (p=0.0001); LDL (p=0.06), HDL (p=0.029) and A1C (p=0.405). Remission of T2DM al 12 months follow-up after surgery was 57% (p=0.124), remission of SAH 37% (p=0.040) and remission of dyslipidemia of 43% (p=0.967).
OAGB is a commonly performed and safe procedure. Short term results appear promising; however, long-term follow-up is necessary to evaluate complications and possible nutritional effects.
肥胖是一个主要的健康问题。单吻合口胃旁路术（OAGB）是一种限制性和吸收不良性减重手术，在作为减重机制方面具有与Roux-en-Y胃旁路术相同的特点；但其结果仍存在争议。
描述OAGB的技术和结果及其对体重减轻和合并症缓解的影响。
回顾性分析2017年1月至2018年1月期间接受OAGB手术的所有患者。记录患者的基线特征。随访常规安排在1、3、6和12个月。
共有51例患者接受了OAGB手术。平均年龄为43.8±9.3岁，平均体重为125±31，平均BMI为55.8±12kg/m²。关于合并症，64.7%患有2型糖尿病（T2DM），43.1%患有系统性动脉高血压（SAH），51%患有血脂异常。12个月时BMI从48.4±1.3降至31±4.4（p=0.0001），随访12个月时平均超重减轻（EWL）为65%。总胆固醇（CT）（p=0.348）、甘油三酯（TGC）（p=0.0001）、低密度脂蛋白（p=0.06）、高密度脂蛋白（p=0.029）和糖化血红蛋白（p=0.405）的值有所改善。术后12个月随访时T2DM缓解率为57%（p=0.124），SAH缓解率为37%（p=0.040），血脂异常缓解率为43%（p=0.967）。
OAGB是一种常见且安全的手术。短期结果似乎很有前景；然而，需要长期随访以评估并发症和可能的营养影响。
