Ladrón-de-Guevara David, Pérez Daniel, Núñez Paulina, Ramírez Felipe, Zárate Alejandro, López Francisco
Departamento de Radiología, Clínica Las Condes, Santiago, Chile.
Departamento de Gastroenterología, Hospital San Juan de Dios, Santiago, Chile.
Rev Med Chil. 2019 Jul;147(7):828-835. doi: 10.4067/S0034-98872019000700828.
Colorectal cancer (CRC) is the third most prevalent cancer in the world and is the second cause of cancer death. Positron emission tomography/computed tomography (PET/CT) using 18F-FDG is used for its staging and follow up.
To assess the occurrence of synchronous colonic and extracolonic tumors detected with contrast-enhanced F18-FDG PET/CT (PET/CTc) in patients with a recently diagnosed CRC.
PET/CTc of 210patients aged 16-91, years (63% men) with a recently diagnosed CRC were reviewed. PET/CTc with incidental findings, not expected to be due to CRC, were followed (laboratory, imaging and pathology) searching for synchronous tumors.
Ten patients (4,7%) had a second synchronous CRC. Only 70% of synchronous CRC were accessible to colonoscopy, due mainly to incomplete procedures for stenotic tumors. Extracolonic synchronous neoplasms were detected in 12 patients (5,7%), namely lung cancer in three, renal cell carcinoma in two, non-Hodgkin lymphoma in two, pancreatic cancer in one, breast cancer in one, hepatocellular carcinoma in one, bladder cancer in one and thyroid cancer in one.
Ten percent of patients with a recently diagnosed CRC had a synchronic neoplasm detected at staging using PET/CTc.
结直肠癌（CRC）是全球第三大常见癌症，也是癌症死亡的第二大原因。使用18F-FDG的正电子发射断层扫描/计算机断层扫描（PET/CT）用于其分期和随访。
评估近期诊断为CRC的患者中，通过对比增强F18-FDG PET/CT（PET/CTc）检测到的同步性结肠和结肠外肿瘤的发生率。
回顾了210例年龄在16 - 91岁（63%为男性）近期诊断为CRC患者的PET/CTc检查结果。对PET/CTc检查中发现的、预期并非由CRC引起的偶然发现进行随访（实验室检查、影像学检查和病理学检查），以寻找同步性肿瘤。
10例患者（4.7%）有第二个同步性CRC。仅70%的同步性CRC可通过结肠镜检查发现，主要原因是狭窄肿瘤的检查程序不完整。在12例患者（5.7%）中检测到结肠外同步性肿瘤，其中肺癌3例、肾细胞癌2例、非霍奇金淋巴瘤2例、胰腺癌1例、乳腺癌1例、肝细胞癌1例、膀胱癌1例和甲状腺癌1例。
近期诊断为CRC的患者中，10%在使用PET/CTc进行分期时检测到同步性肿瘤。
