Rueda Manuel E, Tavares Isabella, López Claudia C, García Juan
Laboratorio de Hongos Entomopatógenos y Control Biológico, Centro de Estudios Parasitológicos y de Vectores (CEPAVE), Universidad Nacional de La Plata-CONICET, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Biomedica. 2019 Dec 1;39(4):798-810. doi: 10.7705/biomedica.4598.
Leptolegnia chapmanii is a facultative pathogen of many species of mosquitoes, among which species of the genus Aedes, Culex and Anopheles stand out for their medical and sanitary importance. The potential of L. chapmanii as an alternative to control lies in its virulence, pathogenicity and specificity against the larval stages of mosquitoes, and because of its harmlessness to non-target species such as fish and amphibians, among others. The natural presence of L. chapmanii had been reported in Argentina, Brazil and the United States. Its presence is possible in other countries throughout the American continent. The development of protocols to produce, formulate, store and apply products based on this microorganism is one of the objectives proposed for the group of Entomopathogenic Fungi at the Centro de Estudios Parasitológicos y de Vectores, Universidad Nacional de La Plata. The efficacy of L. chapmanii as controller is affected by external factors such as temperature, pH, salinity and radiation among others. The process of transfer from the research centers to industry implies many phases. In this way, our project with L. chapmanii is in an initial phase, where we are working on a laboratory scale in proof of concept. We hope to begin soon with the efficacy, efficiency, stability and ecotoxicological safety tests, at the laboratory, semi-field and field scale.
查普曼纤细丝囊霉是多种蚊子的兼性病原菌，其中伊蚊属、库蚊属和按蚊属的蚊子因其在医学和卫生方面的重要性而格外突出。查普曼纤细丝囊霉作为一种控制手段的潜力在于其对蚊子幼虫阶段的毒力、致病性和特异性，以及它对鱼类和两栖动物等非目标物种无害。阿根廷、巴西和美国已报道过查普曼纤细丝囊霉的自然存在情况。在美洲大陆的其他国家也有可能存在。制定基于这种微生物的产品生产、配方、储存和应用方案是拉普拉塔国立大学寄生虫学和病媒研究中心昆虫病原真菌研究小组提出的目标之一。查普曼纤细丝囊霉作为控制剂的功效受温度、pH值、盐度和辐射等外部因素影响。从研究中心向产业转移的过程涉及多个阶段。因此，我们关于查普曼纤细丝囊霉的项目正处于初始阶段，目前我们正在实验室规模上进行概念验证工作。我们希望很快能在实验室、半田间和田间规模上开展功效、效率、稳定性和生态毒理学安全性测试。
