低颅压性头痛中的脑血流量——已知情况有哪些？

Cerebral Blood Flow in Low Intracranial Pressure Headaches-What is Known?

作者信息

Nowaczewska Magdalena, Kaźmierczak Henryk

机构信息

Department of Pathophysiology of Hearing and Balance System, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, M. Curie 9, 85-090 Bydgoszcz, Poland.

Department of Otolaryngology, Head and Neck Surgery, and Laryngological Oncology, Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University, M. Curie 9, 85-090 Bydgoszcz, Poland.

出版信息

Brain Sci. 2019 Dec 19;10(1):2. doi: 10.3390/brainsci10010002.

DOI:10.3390/brainsci10010002

PMID:31861526

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7016724/

Abstract

Headaches attributed to low cerebrospinal fluid (CSF) pressure are described as orthostatic headaches caused by spontaneous or secondary low CSF pressure or CSF leakages. Regardless of the cause, CFS leaks may lead to intracranial hypotension (IH) and influence cerebral blood flow (CBF). When CSF volume decreases, a compensative increase in intracranial blood volume and cerebral vasodilatation occurs. Sinking of the brain and traction on pain-sensitive structures are thought to be the causes of orthostatic headaches. Although there are many studies concerning CBF during intracranial hypertension, little is known about CBF characteristics during low intracranial pressure. The aim of this review is to examine the relationship between CBF, CSF, and intracranial pressure in headaches assigned to low CSF pressure.

摘要

归因于脑脊液（CSF）压力过低的头痛被描述为自发性或继发性脑脊液压力过低或脑脊液漏导致的体位性头痛。无论病因如何，脑脊液漏都可能导致颅内低压（IH）并影响脑血流量（CBF）。当脑脊液量减少时，颅内血容量会发生代偿性增加以及脑血管扩张。脑部下沉和对疼痛敏感结构的牵拉被认为是体位性头痛的原因。尽管有许多关于颅内高压期间脑血流量的研究，但对于颅内低压期间的脑血流量特征却知之甚少。本综述的目的是研究在归因于脑脊液压力过低的头痛中脑血流量、脑脊液和颅内压之间的关系。