Grimaldi D, Mea E, Chiapparini L, Ciceri E, Nappini S, Savoiardo M, Castelli M, Cortelli P, Carriero M R, Leone M, Bussone G
Dipartimento di Neuroscienze, Università di Modena e Reggio Emilia, Italy.
Neurol Sci. 2004 Oct;25 Suppl 3:S135-7. doi: 10.1007/s10072-004-0272-x.
Spontaneous intracranial hypotension (SIH) is a syndrome of low cerebrospinal fluid (CSF) pressure characterised by postural headaches in patients without any history of dural puncture or penetrating trauma. Described by Schaltenbrand in 1938, SIH is thought to result from an occult CSF leak resulting in decreased CSF volume and, consequently, in low CSF pressure. Magnetic resonance imaging of the head and spine has improved the diagnosis of the syndrome showing peculiar radiographic abnormalities including diffuse pachymeningeal enhancement, subdural fluid collections and downward displacement of the cerebral structures. Treatment of SIH headache should start with conservative, non-invasive therapies while epidural blood patch has emerged as the treatment of choice for those symptomatic patients who have failed medical noninvasive approaches.
自发性颅内低压（SIH）是一种脑脊液（CSF）压力降低的综合征，其特征为在没有任何硬膜穿刺或穿透性创伤史的患者中出现体位性头痛。1938年由沙尔滕布兰德描述，SIH被认为是由隐匿性脑脊液漏导致脑脊液量减少，进而导致脑脊液压力降低所致。头部和脊柱的磁共振成像改善了该综合征的诊断，显示出特殊的影像学异常，包括弥漫性硬脑膜强化、硬膜下积液和脑结构向下移位。SIH头痛的治疗应首先采用保守的非侵入性疗法，而硬膜外血贴已成为那些对非侵入性药物治疗无效的有症状患者的首选治疗方法。
