Bystrevskaia V B, Lichkun V V, Antonov A S, Perov N A
Ontogenez. 1988 Jul-Aug;19(4):371-9.
The fine structure of the centriolar system was studied on serial sections of 90 endothelial cells of human aorta (50 to 60 years) in regions without atherosclerotic platelets and with fibrous and atheromatous platelets and of 30 endothelial cells of human embryonic aorta (22-24 weeks). The vast majority (95%) of endothelial cells of the atheromatous platelets were shown to have a primary cilium over 1 micron long which gives on the basal surface in all the cells. In the regions without platelets and with fibrous platelets a cilium was observed in about 20% of cells and it gives in the vessel lumen. Endothelial cells with a cilium fully embedded in the cytoplasm and with abnormal cilium structure were found in the embryonic aorta. A suggestion is put forward that cilia of the endothelial cells of embryonic aorta and those of adult aorta differ by the mechanism of their formation and can have different functions.
在无动脉粥样硬化血小板以及有纤维性和粥样化血小板区域的90个人类主动脉内皮细胞(50至60岁)的连续切片上,以及在人类胚胎主动脉(22 - 24周)的30个内皮细胞上,对中心粒系统的精细结构进行了研究。结果显示,绝大多数(95%)粥样化血小板的内皮细胞具有一根长度超过1微米的初级纤毛,该纤毛在所有细胞的基底面伸出。在无血小板和有纤维性血小板的区域,约20%的细胞中观察到有纤毛,且其伸向血管腔。在胚胎主动脉中发现了纤毛完全嵌入细胞质以及纤毛结构异常的内皮细胞。有人提出,胚胎主动脉和成年主动脉内皮细胞的纤毛在形成机制上存在差异,并且可能具有不同的功能。