Stimson P G, Tortoledo M E, Luna M A, Ordõnez N G
Department of Pathology and Radiology, University of Texas Health Science Center, Houston.
Oral Surg Oral Med Oral Pathol. 1988 Oct;66(4):466-9. doi: 10.1016/0030-4220(88)90270-8.
We report a case of primary amyloid tumor (amyloidoma) of the left parotid gland. To the best of our knowledge this is the first case of this tumor in a parotid gland to be reported in the English literature. Congo red staining with prior potassium permanganate incubation confirmed the localized primary type of amyloid. Immunocytochemical studies demonstrated staining for immunoglobulin A, lambda and kappa light chains within the amyloid deposits and in the cytoplasm of the lymphocytes, and plasma cell aggregates. Ultrastructural examination showed characteristic findings of straight, nonbranching fibrils, measuring 80 to 100 A in length, that were diagnostic of amyloid. The patient had no symptoms and no clinical or laboratory evidence of systemic amyloidosis or multiple myeloma at a 1-year follow-up examination.
我们报告一例左侧腮腺原发性淀粉样瘤（淀粉样瘤）。据我们所知，这是英文文献中首次报道的腮腺发生的该肿瘤病例。先用高锰酸钾孵育后进行刚果红染色，证实为局限性原发性淀粉样变类型。免疫细胞化学研究显示，淀粉样沉积物内以及淋巴细胞和浆细胞聚集物的细胞质中存在免疫球蛋白A、λ和κ轻链染色。超微结构检查显示有特征性表现，即长度为80至100埃的直的、无分支的原纤维，可诊断为淀粉样变。在1年的随访检查中，患者无症状，也没有全身性淀粉样变或多发性骨髓瘤的临床或实验室证据。
