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麻醉期间右美托咪定输注过量:一例报告。

Dexmedetomidine infusion overdose during anesthesia: A case report.

机构信息

University of Melbourne, Parkville, Vic, Australia.

Department of Anaesthesia and Pain Management, Royal Children's Hospital, Parkville, Vic, Australia.

出版信息

Paediatr Anaesth. 2020 Feb;30(2):191-193. doi: 10.1111/pan.13801. Epub 2020 Jan 27.

Abstract

A 12-kg infant was given intravenous dexmedetomidine 0.2 µg kg  min as an adjunct for general anesthesia. The 60-fold increase in dexmedetomidine infusion rate caused a biphasic response with initial hypertension followed by bradycardia and hypotension requiring inotropic support. No postoperative or long-term sequelae were noted. Dexmedetomidine infusion is usually delivered as µg kg  h .

摘要

一名 12 公斤重的婴儿接受了静脉注射右美托咪定 0.2μg/kg/min,作为全身麻醉的辅助用药。右美托咪定输注率增加了 60 倍,导致出现双相反应,最初是高血压,随后是心动过缓和低血压,需要使用正性肌力药物支持。未观察到术后或长期后遗症。右美托咪定输注通常以μg/kg/h 的形式给予。

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