University of Melbourne, Parkville, Vic, Australia.
Department of Anaesthesia and Pain Management, Royal Children's Hospital, Parkville, Vic, Australia.
Paediatr Anaesth. 2020 Feb;30(2):191-193. doi: 10.1111/pan.13801. Epub 2020 Jan 27.
A 12-kg infant was given intravenous dexmedetomidine 0.2 µg kg min as an adjunct for general anesthesia. The 60-fold increase in dexmedetomidine infusion rate caused a biphasic response with initial hypertension followed by bradycardia and hypotension requiring inotropic support. No postoperative or long-term sequelae were noted. Dexmedetomidine infusion is usually delivered as µg kg h .
一名 12 公斤重的婴儿接受了静脉注射右美托咪定 0.2μg/kg/min,作为全身麻醉的辅助用药。右美托咪定输注率增加了 60 倍,导致出现双相反应,最初是高血压,随后是心动过缓和低血压,需要使用正性肌力药物支持。未观察到术后或长期后遗症。右美托咪定输注通常以μg/kg/h 的形式给予。